Cell Trapping by Local Magnetic Force Using Sinewave Magnetic Structure

Chen Yu Huang, Pao Jen Chen, Ke Li Tsai, Jiann Yeu Chen, Teng Fu Hsieh, Zung Hang Wei

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A sine wave magnetic structure with domain wall (DW) pinning geometry is designed to actively trap magnetically labeled cells. After an initial in-plane magnetic field (Hinitial) is applied and later reduced to zero, and the resultant magnetization became locally aligned. Primary mouse embryonic fibroblasts are magnetically labeled by internalizing magnetic nanoparticles (MNPs). Prussian blue stain and single-cell magnetophoresis are performed to evaluate the internalization of the MNPs. The magnetically labeled cells are then trapped by the stray fields of the head-to-head DWs or the tail-to-tail DWs. The magnetic attraction force is estimated to be 0.2-1.3 pN, while the corresponding magnetic gradient is estimated to be 1.64 to 2.1 T/m.

Original languageEnglish
Article number7137652
JournalIEEE Transactions on Magnetics
Volume51
Issue number11
DOIs
Publication statusPublished - 2015 Nov 1

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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