Abstract
Many eukaryotic and prokaryotic cells can exhibit remarkable sensing ability under small gradients of chemical compounds. In this study, we approach this phenomenon by considering the contribution of multiple ligands to the chemical kinetics within the Michaelis-Menten model. This work was inspired by the recent theoretical findings of Hu. Our treatment with practical binding energies and chemical potentials provides results that are consistent with experimental observations.
| Original language | English |
|---|---|
| Article number | 011904 |
| Journal | Physical Review E - Statistical, Nonlinear, and Soft Matter Physics |
| Volume | 85 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2012 Jan 6 |
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All Science Journal Classification (ASJC) codes
- Statistical and Nonlinear Physics
- Statistics and Probability
- Condensed Matter Physics
Cite this
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Cellular ability to sense spatial gradients in the presence of multiple competitive ligands. / Liou, Shu Hao; Chen, Chia Chu.
In: Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, Vol. 85, No. 1, 011904, 06.01.2012.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cellular ability to sense spatial gradients in the presence of multiple competitive ligands
AU - Liou, Shu Hao
AU - Chen, Chia Chu
PY - 2012/1/6
Y1 - 2012/1/6
N2 - Many eukaryotic and prokaryotic cells can exhibit remarkable sensing ability under small gradients of chemical compounds. In this study, we approach this phenomenon by considering the contribution of multiple ligands to the chemical kinetics within the Michaelis-Menten model. This work was inspired by the recent theoretical findings of Hu. Our treatment with practical binding energies and chemical potentials provides results that are consistent with experimental observations.
AB - Many eukaryotic and prokaryotic cells can exhibit remarkable sensing ability under small gradients of chemical compounds. In this study, we approach this phenomenon by considering the contribution of multiple ligands to the chemical kinetics within the Michaelis-Menten model. This work was inspired by the recent theoretical findings of Hu. Our treatment with practical binding energies and chemical potentials provides results that are consistent with experimental observations.
UR - http://www.scopus.com/inward/record.url?scp=84863025477&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84863025477&partnerID=8YFLogxK
U2 - 10.1103/PhysRevE.85.011904
DO - 10.1103/PhysRevE.85.011904
M3 - Article
C2 - 22400588
AN - SCOPUS:84863025477
VL - 85
JO - Physical review. E
JF - Physical review. E
SN - 1539-3755
IS - 1
M1 - 011904
ER -