Cellular ability to sense spatial gradients in the presence of multiple competitive ligands

Shu Hao Liou, Chia Chu Chen

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Many eukaryotic and prokaryotic cells can exhibit remarkable sensing ability under small gradients of chemical compounds. In this study, we approach this phenomenon by considering the contribution of multiple ligands to the chemical kinetics within the Michaelis-Menten model. This work was inspired by the recent theoretical findings of Hu. Our treatment with practical binding energies and chemical potentials provides results that are consistent with experimental observations.

Original languageEnglish
Article number011904
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume85
Issue number1
DOIs
Publication statusPublished - 2012 Jan 6

All Science Journal Classification (ASJC) codes

  • Statistical and Nonlinear Physics
  • Statistics and Probability
  • Condensed Matter Physics

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