Cellular force measurement in cardiac myocytes using polymer micropillar array with viscoelastic characterization

I. Kuan Lin, Kuang Shun Ou, Kuo-Shen Chen, Xin Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The mechanical properties of Polydimethylsiloxane (PDMS) were characterized by using uniaxial compression, dynamic mechanical analysis (DMA), and nanoindentation tests, as well as finite element method (FEM). A generalized Maxwell model with two exponential terms was used to emulate the mechanical behavior of PDMS at room temperature. After we found the viscoelastic constitutive law of PDMS, we used it to develop a more accurate model for converting deflection data to cellular traction forces.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages269-271
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09-11-0109-11-05

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Lin, I. K., Ou, K. S., Chen, K-S., & Zhang, X. (2009). Cellular force measurement in cardiac myocytes using polymer micropillar array with viscoelastic characterization. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 269-271). Chemical and Biological Microsystems Society.