Characteristics of Hospitalized Patients with Atrial Fibrillation in Taiwan: A Nationwide Observation

Cheng Han Lee, Ping Yen Liu, Liang Miin Tsai, Wei Chuan Tsai, Ming Tsung Ho, Jyh Hong Chen, Li Jen Lin

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Purpose: The aim of the study is to describe the nationwide epidemiological data for hospitalized patients with atrial fibrillation in Taiwan. Methods: We collected information on hospitalized patients with discharge-diagnosed atrial fibrillation from 1997 through 2002 from the Taiwan National Health Insurance database. Patients were examined for temporal trends in the frequency of the disease, clinical characteristics, and in-hospital mortality. Results: Of 162,340 patients (mean age, 73.8 years), 55.3% were men and 38.6% had a primary diagnosis of atrial fibrillation. The mean annual frequency of diagnosed atrial fibrillation was 127 per 100,000 persons. The frequency of atrial fibrillation rose from 91 (1997) to 150 (2002) per 100,000 persons (P <.001); it significantly increased directly with age from 4 per 100,000 in patients <50 years to 1571 per 100,000 in patients ≥80 years. The frequency was significantly higher in men than in women (137 vs 116 per 100,000; P <.001). The average in-hospital mortality rate was 9.3%. In-hospital mortality rate showed a decreasing trend (9.9% vs 7.6%; P = .003). Comorbidities of ischemic heart disease, valvular heart disease, hypertension, ischemic stroke, and congestive heart failure were predictors of higher mortality. Conclusions: This Taiwanese study showed a 1.65-fold increase in the frequency of diagnosed atrial fibrillation during the study period. The in-hospital mortality rate, however, declined. The frequency of atrial fibrillation was higher in men and the elderly. We should be more concerned about negative outcomes in hospitalized patients with atrial fibrillation and other coexisting cardiovascular conditions.

Original languageEnglish
Pages (from-to)819.e1-819.e7
JournalAmerican Journal of Medicine
Volume120
Issue number9
DOIs
Publication statusPublished - 2007 Sep 1

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Taiwan
Atrial Fibrillation
Observation
Hospital Mortality
Mortality
Heart Valve Diseases
Patient Discharge
National Health Programs
Myocardial Ischemia
Comorbidity
Heart Failure
Stroke
Databases
Hypertension

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lee, Cheng Han ; Liu, Ping Yen ; Tsai, Liang Miin ; Tsai, Wei Chuan ; Ho, Ming Tsung ; Chen, Jyh Hong ; Lin, Li Jen. / Characteristics of Hospitalized Patients with Atrial Fibrillation in Taiwan : A Nationwide Observation. In: American Journal of Medicine. 2007 ; Vol. 120, No. 9. pp. 819.e1-819.e7.
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abstract = "Purpose: The aim of the study is to describe the nationwide epidemiological data for hospitalized patients with atrial fibrillation in Taiwan. Methods: We collected information on hospitalized patients with discharge-diagnosed atrial fibrillation from 1997 through 2002 from the Taiwan National Health Insurance database. Patients were examined for temporal trends in the frequency of the disease, clinical characteristics, and in-hospital mortality. Results: Of 162,340 patients (mean age, 73.8 years), 55.3{\%} were men and 38.6{\%} had a primary diagnosis of atrial fibrillation. The mean annual frequency of diagnosed atrial fibrillation was 127 per 100,000 persons. The frequency of atrial fibrillation rose from 91 (1997) to 150 (2002) per 100,000 persons (P <.001); it significantly increased directly with age from 4 per 100,000 in patients <50 years to 1571 per 100,000 in patients ≥80 years. The frequency was significantly higher in men than in women (137 vs 116 per 100,000; P <.001). The average in-hospital mortality rate was 9.3{\%}. In-hospital mortality rate showed a decreasing trend (9.9{\%} vs 7.6{\%}; P = .003). Comorbidities of ischemic heart disease, valvular heart disease, hypertension, ischemic stroke, and congestive heart failure were predictors of higher mortality. Conclusions: This Taiwanese study showed a 1.65-fold increase in the frequency of diagnosed atrial fibrillation during the study period. The in-hospital mortality rate, however, declined. The frequency of atrial fibrillation was higher in men and the elderly. We should be more concerned about negative outcomes in hospitalized patients with atrial fibrillation and other coexisting cardiovascular conditions.",
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Characteristics of Hospitalized Patients with Atrial Fibrillation in Taiwan : A Nationwide Observation. / Lee, Cheng Han; Liu, Ping Yen; Tsai, Liang Miin; Tsai, Wei Chuan; Ho, Ming Tsung; Chen, Jyh Hong; Lin, Li Jen.

In: American Journal of Medicine, Vol. 120, No. 9, 01.09.2007, p. 819.e1-819.e7.

Research output: Contribution to journalArticle

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AU - Ho, Ming Tsung

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N2 - Purpose: The aim of the study is to describe the nationwide epidemiological data for hospitalized patients with atrial fibrillation in Taiwan. Methods: We collected information on hospitalized patients with discharge-diagnosed atrial fibrillation from 1997 through 2002 from the Taiwan National Health Insurance database. Patients were examined for temporal trends in the frequency of the disease, clinical characteristics, and in-hospital mortality. Results: Of 162,340 patients (mean age, 73.8 years), 55.3% were men and 38.6% had a primary diagnosis of atrial fibrillation. The mean annual frequency of diagnosed atrial fibrillation was 127 per 100,000 persons. The frequency of atrial fibrillation rose from 91 (1997) to 150 (2002) per 100,000 persons (P <.001); it significantly increased directly with age from 4 per 100,000 in patients <50 years to 1571 per 100,000 in patients ≥80 years. The frequency was significantly higher in men than in women (137 vs 116 per 100,000; P <.001). The average in-hospital mortality rate was 9.3%. In-hospital mortality rate showed a decreasing trend (9.9% vs 7.6%; P = .003). Comorbidities of ischemic heart disease, valvular heart disease, hypertension, ischemic stroke, and congestive heart failure were predictors of higher mortality. Conclusions: This Taiwanese study showed a 1.65-fold increase in the frequency of diagnosed atrial fibrillation during the study period. The in-hospital mortality rate, however, declined. The frequency of atrial fibrillation was higher in men and the elderly. We should be more concerned about negative outcomes in hospitalized patients with atrial fibrillation and other coexisting cardiovascular conditions.

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