TY - GEN
T1 - Characterization of the colorectal cancer in a rabbit model using quantitative high-frequency endoscopic ultrasound
AU - Liu, Cheng
AU - Yang, Yaoheng
AU - Sun, Lei
AU - Huang, Chih Chung
PY - 2013
Y1 - 2013
N2 - Colorectal cancer (CRC) at early stage often has no symptoms, which causes delay of successful treatments. Colonoscopy is clinically performed for screening, during which biopsy may be conducted; however, it is difficult to determine early stage CRC by ordinary endoscopy even with dye due to the insufficient superficial scope of colorectal surface for pre-cancerous diagnosis. Endoscopic ultrasound (EUS) has been widely used to visualize overall depth-view five-layered structural alteration of colorectal tract. The field of knowledge of high-frequency EUS with quantitative ultrasound (QUS) for early colorectal cancer diagnosis is yet to be fully determined and a reproducible and feasible animal model is appropriate for further development of this novel modality. VX2 CRC Rabbit model is first time used as a model for endoscopic ultrasound imaging according to our knowledge. In this study, we for the first time show the application of high-frequency EUS along with QUS to characterize malignant colorectal tumor and benign colorectal tissue in a rabbit model of VX2 colorectal cancer.
AB - Colorectal cancer (CRC) at early stage often has no symptoms, which causes delay of successful treatments. Colonoscopy is clinically performed for screening, during which biopsy may be conducted; however, it is difficult to determine early stage CRC by ordinary endoscopy even with dye due to the insufficient superficial scope of colorectal surface for pre-cancerous diagnosis. Endoscopic ultrasound (EUS) has been widely used to visualize overall depth-view five-layered structural alteration of colorectal tract. The field of knowledge of high-frequency EUS with quantitative ultrasound (QUS) for early colorectal cancer diagnosis is yet to be fully determined and a reproducible and feasible animal model is appropriate for further development of this novel modality. VX2 CRC Rabbit model is first time used as a model for endoscopic ultrasound imaging according to our knowledge. In this study, we for the first time show the application of high-frequency EUS along with QUS to characterize malignant colorectal tumor and benign colorectal tissue in a rabbit model of VX2 colorectal cancer.
UR - http://www.scopus.com/inward/record.url?scp=84894382785&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84894382785&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2013.0229
DO - 10.1109/ULTSYM.2013.0229
M3 - Conference contribution
AN - SCOPUS:84894382785
SN - 9781467356862
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 891
EP - 894
BT - 2013 IEEE International Ultrasonics Symposium, IUS 2013
T2 - 2013 IEEE International Ultrasonics Symposium, IUS 2013
Y2 - 21 July 2013 through 25 July 2013
ER -