Abstract
A new biscoumarin, namely citrumedin-A [6,6′,7,7′-tetramethoxy-3,3′-biscoumarin] (1), together with twenty two known compounds were isolated from the stem bark of Citrus medica L. var. sarcodactylis Swingle. The structure of this new compound was completely elucidated using a combination of 2D NMR techniques (COSY, NOESY, HMQC and HMBC) and HR-EI-MS analyses. The known compounds were identified by comparison of their spectroscopic and physical data with those reported in the literatures. The isolates were also screened their cytotoxicity against Daoy, Hep2, MCF-7 and Hela cell lines. Lonchocarpol A (12) showed marginally cytotoxic activity against those four cancer cell lines.
Original language | English |
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Pages (from-to) | 1309-1316 |
Number of pages | 8 |
Journal | Heterocycles |
Volume | 78 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2009 May 1 |
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Pharmacology
- Organic Chemistry