Chitosan microfiber fabrication using microfluidic chips of different sheath channel angles and its application on cell culture

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we successfully produced the chitosan microfibers using the proposed various angles of microfluidic chip, which was also been simulated. By controlling the core and sheath flow rates, we were able to generate laminar flow of different diameters from 15 μm to 40 μm. And the diameter of chitosan microfiber was measured from 20 μm to 50 μm. The microchannel of angle 30° could produce chitosan laminar flow of a smaller diameter than the angle 60° and angle 45° at the fixed flow rates. Finally, the chitosan microfiber was chosen as scaffold and the schwann cell and fibroblast cell with chitosan microfibers were used for cell culture to test effect in tissue engineering application.

Original languageEnglish
Title of host publicationTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages378-381
Number of pages4
DOIs
Publication statusPublished - 2009 Dec 11
EventTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States
Duration: 2009 Jun 212009 Jun 25

Publication series

NameTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Other

OtherTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
CountryUnited States
CityDenver, CO
Period09-06-2109-06-25

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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    Yeh, C-S., Lin, P. W., & Lin, Y-C. (2009). Chitosan microfiber fabrication using microfluidic chips of different sheath channel angles and its application on cell culture. In TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 378-381). [5285485] (TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems). https://doi.org/10.1109/SENSOR.2009.5285485