Cholesterol biosensor based on nanoporous zinc oxide modified electrodes

Chia-Yu Lin, Kuo Chuan Ho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nanostructured ZnO modified electrodes have been fabricated by co-electrodeposition with eosin Y onto Fdoped SnO2 (FTO) coated glass, and their application for cholesterol biosensor was studied. For cholesterol application, cholesterol oxidase (ChOx) was immobilized onto the ZnO/FTO electrode via physical adsorption. Cyclic voltammetric measurements showed that the ChOx/ZnO/FTO is sensitive to cholesterol and the optimal solution pH for the ChOx/ZnO/FTO electrode for detecting cholesterol was 6.7. Besides, the redox peak current densities are proportional to the square root of scan rate, or v1/2, indicating the electron-transfer process is diffusion limited. The sensitivity, linear detection range, and the limit of detection for the ChOx/ZnO/FTO electrode are 3.01 mA-cm2-M-1, 1.1~4.83 mM, and 20 uM, respectively.

Original languageEnglish
Title of host publicationOlfaction and Electronic Nose - Proceedings of the 13th International Symposium on Olfaction and Electronic Nose, ISOEN
Pages123-126
Number of pages4
DOIs
Publication statusPublished - 2009 Nov 27
Event13th International Symposium on Olfaction and Electronic Nose, ISOEN - Brescia, Italy
Duration: 2009 Apr 152009 Apr 17

Publication series

NameAIP Conference Proceedings
Volume1137
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other13th International Symposium on Olfaction and Electronic Nose, ISOEN
CountryItaly
CityBrescia
Period09-04-1509-04-17

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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  • Cite this

    Lin, C-Y., & Ho, K. C. (2009). Cholesterol biosensor based on nanoporous zinc oxide modified electrodes. In Olfaction and Electronic Nose - Proceedings of the 13th International Symposium on Olfaction and Electronic Nose, ISOEN (pp. 123-126). (AIP Conference Proceedings; Vol. 1137). https://doi.org/10.1063/1.3156487