Clinical implications of left atrial appendage flow patterns in nonrheumatic atrial fibrillation

Yi-Heng Li, L. P. Lai, K. G. Shyu, J. J. Hwang, P. Kuan, W. P. Lien

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Left atrial appendage (LAA) function and flow patterns in 29 patients with chronic nonrheumatic atrial fibrillation were studied by transesophageal echocardiography. These 29 patients (16 men and 13 women; mean age, 63.8 years; range, 38 to 77 years) were classified into two groups according to different LAA flow patterns. Seventeen patients (group 1) had well-defined LAA emptying and filling Doppler flow signals, and the other 12 patients (group 2) had very low LAA flow signals. No significant differences were found in age, sex, mean duration of atrial fibrillation, left ventricular end diastolic dimension, and left ventricular ejection fraction between the two groups. However, group 2 patients had larger left atrial diameter (42.8 ± 4.2 mm vs 36.6 ± 8.8 mm; p < 0.05), lower LAA ejection fraction (26.4 ± 15.2 percent vs 42.6 ± 14.1 percent; p < 0.05), and lower LAA peak emptying velocity (0.13 ± 0.03 m/s vs 0.36 ± 0.16 m/s; p < 0.001). Higher incidence of LAA spontaneous echocardiographic contrast formation in group 2 patients (8/12 vs 1/17; p < 0.001) was noted. In conclusion, a subset of patients with nonrheumatic atrial fibrillation were found to have lower LAA blood flow and poorer LAA function. These patients had higher incidence of left atrial or LAA spontaneous echo contrast formation which had been proved previously to be a marker for future systemic thromboembolism.

Original languageEnglish
Pages (from-to)748-752
Number of pages5
JournalChest
Volume105
Issue number3
DOIs
Publication statusPublished - 1994 Jan 1

Fingerprint

Atrial Appendage
Atrial Fibrillation
Left Atrial Function
Thromboembolism
Transesophageal Echocardiography
Incidence
Stroke Volume

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Li, Yi-Heng ; Lai, L. P. ; Shyu, K. G. ; Hwang, J. J. ; Kuan, P. ; Lien, W. P. / Clinical implications of left atrial appendage flow patterns in nonrheumatic atrial fibrillation. In: Chest. 1994 ; Vol. 105, No. 3. pp. 748-752.
@article{05bf9470411a482c944d69afe24d9e5b,
title = "Clinical implications of left atrial appendage flow patterns in nonrheumatic atrial fibrillation",
abstract = "Left atrial appendage (LAA) function and flow patterns in 29 patients with chronic nonrheumatic atrial fibrillation were studied by transesophageal echocardiography. These 29 patients (16 men and 13 women; mean age, 63.8 years; range, 38 to 77 years) were classified into two groups according to different LAA flow patterns. Seventeen patients (group 1) had well-defined LAA emptying and filling Doppler flow signals, and the other 12 patients (group 2) had very low LAA flow signals. No significant differences were found in age, sex, mean duration of atrial fibrillation, left ventricular end diastolic dimension, and left ventricular ejection fraction between the two groups. However, group 2 patients had larger left atrial diameter (42.8 ± 4.2 mm vs 36.6 ± 8.8 mm; p < 0.05), lower LAA ejection fraction (26.4 ± 15.2 percent vs 42.6 ± 14.1 percent; p < 0.05), and lower LAA peak emptying velocity (0.13 ± 0.03 m/s vs 0.36 ± 0.16 m/s; p < 0.001). Higher incidence of LAA spontaneous echocardiographic contrast formation in group 2 patients (8/12 vs 1/17; p < 0.001) was noted. In conclusion, a subset of patients with nonrheumatic atrial fibrillation were found to have lower LAA blood flow and poorer LAA function. These patients had higher incidence of left atrial or LAA spontaneous echo contrast formation which had been proved previously to be a marker for future systemic thromboembolism.",
author = "Yi-Heng Li and Lai, {L. P.} and Shyu, {K. G.} and Hwang, {J. J.} and P. Kuan and Lien, {W. P.}",
year = "1994",
month = "1",
day = "1",
doi = "10.1378/chest.105.3.748",
language = "English",
volume = "105",
pages = "748--752",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "3",

}

Clinical implications of left atrial appendage flow patterns in nonrheumatic atrial fibrillation. / Li, Yi-Heng; Lai, L. P.; Shyu, K. G.; Hwang, J. J.; Kuan, P.; Lien, W. P.

In: Chest, Vol. 105, No. 3, 01.01.1994, p. 748-752.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinical implications of left atrial appendage flow patterns in nonrheumatic atrial fibrillation

AU - Li, Yi-Heng

AU - Lai, L. P.

AU - Shyu, K. G.

AU - Hwang, J. J.

AU - Kuan, P.

AU - Lien, W. P.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Left atrial appendage (LAA) function and flow patterns in 29 patients with chronic nonrheumatic atrial fibrillation were studied by transesophageal echocardiography. These 29 patients (16 men and 13 women; mean age, 63.8 years; range, 38 to 77 years) were classified into two groups according to different LAA flow patterns. Seventeen patients (group 1) had well-defined LAA emptying and filling Doppler flow signals, and the other 12 patients (group 2) had very low LAA flow signals. No significant differences were found in age, sex, mean duration of atrial fibrillation, left ventricular end diastolic dimension, and left ventricular ejection fraction between the two groups. However, group 2 patients had larger left atrial diameter (42.8 ± 4.2 mm vs 36.6 ± 8.8 mm; p < 0.05), lower LAA ejection fraction (26.4 ± 15.2 percent vs 42.6 ± 14.1 percent; p < 0.05), and lower LAA peak emptying velocity (0.13 ± 0.03 m/s vs 0.36 ± 0.16 m/s; p < 0.001). Higher incidence of LAA spontaneous echocardiographic contrast formation in group 2 patients (8/12 vs 1/17; p < 0.001) was noted. In conclusion, a subset of patients with nonrheumatic atrial fibrillation were found to have lower LAA blood flow and poorer LAA function. These patients had higher incidence of left atrial or LAA spontaneous echo contrast formation which had been proved previously to be a marker for future systemic thromboembolism.

AB - Left atrial appendage (LAA) function and flow patterns in 29 patients with chronic nonrheumatic atrial fibrillation were studied by transesophageal echocardiography. These 29 patients (16 men and 13 women; mean age, 63.8 years; range, 38 to 77 years) were classified into two groups according to different LAA flow patterns. Seventeen patients (group 1) had well-defined LAA emptying and filling Doppler flow signals, and the other 12 patients (group 2) had very low LAA flow signals. No significant differences were found in age, sex, mean duration of atrial fibrillation, left ventricular end diastolic dimension, and left ventricular ejection fraction between the two groups. However, group 2 patients had larger left atrial diameter (42.8 ± 4.2 mm vs 36.6 ± 8.8 mm; p < 0.05), lower LAA ejection fraction (26.4 ± 15.2 percent vs 42.6 ± 14.1 percent; p < 0.05), and lower LAA peak emptying velocity (0.13 ± 0.03 m/s vs 0.36 ± 0.16 m/s; p < 0.001). Higher incidence of LAA spontaneous echocardiographic contrast formation in group 2 patients (8/12 vs 1/17; p < 0.001) was noted. In conclusion, a subset of patients with nonrheumatic atrial fibrillation were found to have lower LAA blood flow and poorer LAA function. These patients had higher incidence of left atrial or LAA spontaneous echo contrast formation which had been proved previously to be a marker for future systemic thromboembolism.

UR - http://www.scopus.com/inward/record.url?scp=0028348290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028348290&partnerID=8YFLogxK

U2 - 10.1378/chest.105.3.748

DO - 10.1378/chest.105.3.748

M3 - Article

VL - 105

SP - 748

EP - 752

JO - Chest

JF - Chest

SN - 0012-3692

IS - 3

ER -