Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis

Kuanfu Chen; Tung Chien Chen; Kimberly Cockerham; Wentai Liu

doi:10.1109/ISCAS.2009.5117807

Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis

Kuanfu Chen, Tung Chien Chen, Kimberly Cockerham, Wentai Liu

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

27 Citations (Scopus)

Abstract

Electrical stimulation in eyelid reanimation has been verified in previous studies as a potential treatment for facial nerve paralysis. Design challenges, including physical pain during stimulation, reducing the latency between the natural blink and the artificial blink, and patient-to-patient differences, make it difficult to build this system. In this paper, the design challenges are analyzed in detail, based on which a closed-loop electrochemical stimulation system is proposed. Using our system, real-time blink detection and electrical stimulation have been verified with FPGA and ASICs. Area of the proposed fully integrated chip, including electromyography (EMG) amplifier, blink detection processor, reduced instruction set computer (RISC), and current stimulator, is estimated to be 11.46mm ² in 0.35um CMOS process.

Original language	English
Title of host publication	2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009
Pages	549-552
Number of pages	4
DOIs	https://doi.org/10.1109/ISCAS.2009.5117807
Publication status	Published - 2009
Event	2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009 - Taipei, Taiwan Duration: 2009 May 24 → 2009 May 27

Publication series

Name	Proceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)	0271-4310

Other

Other	2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009
Country/Territory	Taiwan
City	Taipei
Period	09-05-24 → 09-05-27

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering

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10.1109/ISCAS.2009.5117807

Cite this

Chen, K., Chen, T. C., Cockerham, K., & Liu, W. (2009). Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis. In 2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009 (pp. 549-552). Article 5117807 (Proceedings - IEEE International Symposium on Circuits and Systems). https://doi.org/10.1109/ISCAS.2009.5117807

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title = "Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis",

abstract = "Electrical stimulation in eyelid reanimation has been verified in previous studies as a potential treatment for facial nerve paralysis. Design challenges, including physical pain during stimulation, reducing the latency between the natural blink and the artificial blink, and patient-to-patient differences, make it difficult to build this system. In this paper, the design challenges are analyzed in detail, based on which a closed-loop electrochemical stimulation system is proposed. Using our system, real-time blink detection and electrical stimulation have been verified with FPGA and ASICs. Area of the proposed fully integrated chip, including electromyography (EMG) amplifier, blink detection processor, reduced instruction set computer (RISC), and current stimulator, is estimated to be 11.46mm 2 in 0.35um CMOS process.",

author = "Kuanfu Chen and Chen, {Tung Chien} and Kimberly Cockerham and Wentai Liu",

year = "2009",

doi = "10.1109/ISCAS.2009.5117807",

language = "English",

isbn = "9781424438280",

series = "Proceedings - IEEE International Symposium on Circuits and Systems",

pages = "549--552",

booktitle = "2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009",

note = "2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009 ; Conference date: 24-05-2009 Through 27-05-2009",

}

Chen, K, Chen, TC, Cockerham, K & Liu, W 2009, Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis. in 2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009., 5117807, Proceedings - IEEE International Symposium on Circuits and Systems, pp. 549-552, 2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009, Taipei, Taiwan, 09-05-24. https://doi.org/10.1109/ISCAS.2009.5117807

Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis. / Chen, Kuanfu; Chen, Tung Chien; Cockerham, Kimberly et al.
2009 IEEE International Symposium on Circuits and Systems, ISCAS 2009. 2009. p. 549-552 5117807 (Proceedings - IEEE International Symposium on Circuits and Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - Electrical stimulation in eyelid reanimation has been verified in previous studies as a potential treatment for facial nerve paralysis. Design challenges, including physical pain during stimulation, reducing the latency between the natural blink and the artificial blink, and patient-to-patient differences, make it difficult to build this system. In this paper, the design challenges are analyzed in detail, based on which a closed-loop electrochemical stimulation system is proposed. Using our system, real-time blink detection and electrical stimulation have been verified with FPGA and ASICs. Area of the proposed fully integrated chip, including electromyography (EMG) amplifier, blink detection processor, reduced instruction set computer (RISC), and current stimulator, is estimated to be 11.46mm 2 in 0.35um CMOS process.

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Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis

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