Clostridium difficile Bacteremia, Taiwan

Nan Yao Lee, Yu Tsung Huang, Po Ren Hsueh, Wen Chien Ko

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

To determine clinical characteristics and outcome of patients with Clostridium difficile bacteremia (CDB), we identify ed 12 patients with CDB in 2 medical centers in Taiwan; all had underlying systemic diseases. Five had gastrointestinal diseases or conditions, including pseudomembranous colitis (2 patients); 4 recalled diarrhea, but only 5 had recent exposure to antimicrobial drugs. Ten available isolates were susceptible to metronidazole and vancomycin. Five isolates had C. difficile toxin A or B. Of 5 patients who died, 3 died of CDB. Of 8 patients treated with metronidazole or vancomycin, only 1 died, and all 4 patients treated with other drugs died (12.5% vs. 100%; p = 0.01). C. difficile bacteremia, although uncommon, is thus associated with substantial illness and death rates.

Original languageEnglish
Pages (from-to)1204-1210
Number of pages7
JournalEmerging infectious diseases
Volume16
Issue number8
DOIs
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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