CO 2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids

Wei Peng Li, Chia Hao Su, Sheng Jung Wang, Fu Ju Tsai, Chun Ting Chang, Min Chiao Liao, Chun Chieh Yu, Thi Tuong Vi Tran, Chaw-Ning Lee, Wen-Tai Chiu, Tak-Wah Wong, Chen-Sheng Yeh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Traditional wound care methods include wound infection control, adequate nutritional supplements, education of changing position every 2-3 h to avoid tissue hypoxia, vacuum assistant closure, debridement, skin graft, and tissue flap. Electric current stimulation, ultrasound, laser, and hydrotherapy have emerged as adjuvant therapies. However, most, if not all, of these therapies are expensive, and the treatment results are variable. The development of the active methods to improve wound healing is mandatory. CO 2 administration has been known to improve microcirculation and local oxygen supply that are beneficial to wound healing. Here, the metal ion-ligand coordination nanoarchitecture was designed to reveal NIR light-induced CO 2 generation for wound healing. The administration simply topically dropped the colloidal solution on the incisional wound, followed by exposure of near-infrared (NIR) lamp to yield CO 2 , resulting in the observation of the accelerated wound healing.

Original languageEnglish
Pages (from-to)5826-5835
Number of pages10
JournalACS Nano
Volume11
Issue number6
DOIs
Publication statusPublished - 2017 Jun 27

Fingerprint

Infrared lamps
wound healing
Colloids
Carbon Monoxide
luminaires
colloids
delivery
Irradiation
Tissue
Physical therapy
Microcirculation
Oxygen supply
irradiation
Electric currents
Grafts
Metal ions
skin grafts
therapy
Skin
Education

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Li, Wei Peng ; Su, Chia Hao ; Wang, Sheng Jung ; Tsai, Fu Ju ; Chang, Chun Ting ; Liao, Min Chiao ; Yu, Chun Chieh ; Vi Tran, Thi Tuong ; Lee, Chaw-Ning ; Chiu, Wen-Tai ; Wong, Tak-Wah ; Yeh, Chen-Sheng. / CO 2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids In: ACS Nano. 2017 ; Vol. 11, No. 6. pp. 5826-5835.
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CO 2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids . / Li, Wei Peng; Su, Chia Hao; Wang, Sheng Jung; Tsai, Fu Ju; Chang, Chun Ting; Liao, Min Chiao; Yu, Chun Chieh; Vi Tran, Thi Tuong; Lee, Chaw-Ning; Chiu, Wen-Tai; Wong, Tak-Wah; Yeh, Chen-Sheng.

In: ACS Nano, Vol. 11, No. 6, 27.06.2017, p. 5826-5835.

Research output: Contribution to journalArticle

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