Cobalt oxide acicular nanorods with high sensitivity for the non-enzymatic detection of glucose

Chung Wei Kung, Chia Yu Lin, Yi Hsuan Lai, R. Vittal, Kuo Chuan Ho

Research output: Contribution to journalArticlepeer-review

170 Citations (Scopus)


Acicular cobalt oxide nanorods (CoONRs) were prepared for the non-enzymatic detection of glucose, first by directly growing layered cobalt carbonate hydroxide (LCCH) on a conducting fluorine-doped tin oxide (FTO) substrate using a simple chemical bath deposition (CBD) technique and then by transforming the LCCH into CoONRs through pyrolysis. The composition and grain size of the films of LCCH and CoONRs were verified by X-ray diffraction (XRD); their morphologies were examined by scanning electron microscopic (SEM) and transmission electron microscopic (TEM) images. CoONRs showed high electrocatalytic activity for the electro-oxidation of glucose in alkaline media, and the activity was strongly influenced by NaOH concentration, annealing temperature of CoONRs, and thickness of CoONRs film. The pertinent sensor could be successfully used for the quantification of glucose by amperometric method. The sensing parameters include wide linear range up to 3.5mM, a high sensitivity of 571.8μA/(cm 2mM), and a remarkable low detection limit of 0.058μM. The CoONRs modified electrode exhibited a high selectivity for glucose in human serum, against ascorbic acid, uric acid, and acetaminophen.

Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalBiosensors and Bioelectronics
Issue number1
Publication statusPublished - 2011 Sep 15

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry


Dive into the research topics of 'Cobalt oxide acicular nanorods with high sensitivity for the non-enzymatic detection of glucose'. Together they form a unique fingerprint.

Cite this