Colorado Potato Beetle Antifeedants by Simple Modification of the Birchbark Triterpene Betulin

Fu-Yung Huang, Bong Youl Chung, Michael D. Bentley, A. Randall Alford

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Oxidation of the 19-side-chain of betulin 3β,28-diacetate, a pentacyclic triterpene derived from the readily available birchbark triterpene, betulin, yielded compounds active as antifeedants against larvae of the agricultural insect pest Colorado potato beetle, Leptinotarsa decemlineata. Of the eight compounds investigated, the most active was 30-hydroxy-20-oxo-29-norlup-3β,28-diacetate (VI). Acetylation of VI significantly reduced antifeedant activity.

Original languageEnglish
Pages (from-to)2513-2516
Number of pages4
JournalJournal of Agricultural and Food Chemistry
Volume43
Issue number9
DOIs
Publication statusPublished - 1995 Sep 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

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