Comparative analysis of Phytophthora genomes reveals oomycete pathogenesis in crops

Rui Fang Gao, Jie Yu Wang, Ke Wei Liu, Kouki Yoshida, Yu Yun Hsiao, Yi Xiang Shi, Kun Chan Tsai, You Yi Chen, Nobutaka Mitsuda, Chieh Kai Liang, Zhi Wen Wang, Ying Wang, Di Yang Zhang, Laiqiang Huang, Xiang Zhao, Wen Ying Zhong, Ying Hui Cheng, Zi De Jiang, Ming He Li, Wei Hong SunXia Yu, Wenqi Hu, Zhuang Zhou, Xiao Fan Zhou, Chuan Ming Yeh, Kazutaka Katoh, Wen Chieh Tsai, Zhong Jian Liu, Francis Martin, Gui Ming Zhang

Research output: Contribution to journalArticlepeer-review

Abstract

The oomycete genus Phytophthora includes devastating plant pathogens that are found in almost all ecosystems. We sequenced the genomes of two quarantined Phytophthora species–P. fragariae and P. rubi. Comparing these Phytophthora species and related genera allowed reconstruction of the phylogenetic relationships within the genus Phytophthora and revealed Phytophthora genomic features associated with infection and pathogenicity. We found that several hundred Phytophthora genes are putatively inherited from red algae, but Phytophthora does not have vestigial plastids originating from phototrophs. The horizontally-transferred Phytophthora genes are abundant transposons that “transmit” exogenous gene to Phytophthora species thus bring about the gene recombination possibility. Several expansion events of Phytophthora gene families associated with cell wall biogenesis can be used as mutational targets to elucidate gene function in pathogenic interactions with host plants. This work enhanced the understanding of Phytophthora evolution and will also be helpful for the design of phytopathological control strategies. Phytophthora; Genome; Phylogenetic; Pathogenicity; Horizontally gene transfer.

Original languageEnglish
Article numbere06317
JournalHeliyon
Volume7
Issue number2
DOIs
Publication statusPublished - 2021 Feb

All Science Journal Classification (ASJC) codes

  • General

Fingerprint Dive into the research topics of 'Comparative analysis of Phytophthora genomes reveals oomycete pathogenesis in crops'. Together they form a unique fingerprint.

Cite this