Comparison between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related cirrhosis

Han Chieh Lin, Yang Te Tsai, Fa Yauh Lee, Ting Tsung Chang, Sun Sang Wang, Chii Shyan Lay, Shou Dong Lee, Kwang Juei Lo

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Portal vein pressure and wedged hepatic vein pressure were measured simultaneously in 21 patients with hepatitis B-related cirrhosis of the liver and were compared to pressure measured in six patients with idiopathic portal hypertension. No significant difference in the portal venous pressure gradient was found between patients with cirrhosis and those with idiopathic portal hypertension (17.3 ± 4.3 mmHg (mean ± S.D.) vs. 19.7 ± 3.1 mmHg, P > 0.05). However, the difference between the portal and the hepatic venous pressure gradient was significantly smaller in patients with cirrhosis than in idiopathic portal hypertension patients (1.3 ± 1.7 vs. 10.8 ± 2.1 mmHg, P < 0.001). An excellent correlation was found between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related cirrhosis (r = 0.94, P < 0.001). There was no linear relationship between the portal venous pressure gradient and varix size or bleeding episodes. We concluded that a close agreement existed between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related liver cirrhosis. Therefore, measurement of wedged hepatic vein pressure reliably reflects portal vein pressure in these patients.

Original languageEnglish
Pages (from-to)326-330
Number of pages5
JournalJournal of Hepatology
Volume9
Issue number3
DOIs
Publication statusPublished - 1989 Nov

All Science Journal Classification (ASJC) codes

  • Hepatology

Fingerprint Dive into the research topics of 'Comparison between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related cirrhosis'. Together they form a unique fingerprint.

  • Cite this