Constituents and cytotoxic principles of Nothapodytes foetida

Tian Shung Wu, Yann Lii Leu, Hua Chun Hsu, Li Fei Ou, Chien Chih Chen, Chieh Fu Chen, Jun Chih Ou, Yang Chang Wu

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51 Citations (Scopus)

Abstract

A new naturally occurring alkaloid, acetylcamptothecin, together with 17 known compounds, (+)-1-hydroxypinoresinol, ω-hydroxypropioguaiacone, p-hydroxybenzaldehyde, scopoletin, uracil, thymine, sitosterol, sitosteryl-β-d-glucoside, 3β-hydroxy-stigmast-5-en-7-one, stigmast-5-en-3β,7α-diol, 6β-hydroxystigmast-4-en-3-one, sitost-4-en-3-one, linoleic acid, trigonelline, camptothecin, 9-O-methoxycamptothecin and pumiloside were isolated and characterized from the stem of Nothapodytes foetida. Among them, scopoletin, camptothecin, 9-O-methoxycamptothecin and O-acetylcamptothecin showed significant cytotoxic activity.

Original languageEnglish
Pages (from-to)383-385
Number of pages3
JournalPhytochemistry
Volume39
Issue number2
DOIs
Publication statusPublished - 1995 May

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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    Wu, T. S., Leu, Y. L., Hsu, H. C., Ou, L. F., Chen, C. C., Chen, C. F., Ou, J. C., & Wu, Y. C. (1995). Constituents and cytotoxic principles of Nothapodytes foetida. Phytochemistry, 39(2), 383-385. https://doi.org/10.1016/0031-9422(94)00901-5