@article{13d19c66117f484189f1092806408b8d,
title = "Constituents from the leaves of Clausena lansium and their anti-inflammatory activity",
abstract = "Five new acyclic amides, clausenalansamides C-G (1–5), clausenaline G (6) and (±)-5-(4-methylphenyl)-γ-valerolactone (7) reported from the natural source for the first time, were characterized from the leaves of Clausena lansium. Their structures were established by spectroscopic and spectrometric methods, and the absolute configurations of new compounds 1–5 were determined by electronic circular dichroism and single-crystal X-ray diffraction analyses. Eighteen compounds were evaluated for their anti-inflammatory activity and only imperatorin (11) and wampetin (12) displayed significant inhibition of fMLP/CB-induced superoxide anion generation with IC50 values of 1.7 ± 0.3 and 6.8 ± 1.1 μM, respectively.",
author = "Shen, {De Yang} and Kuo, {Ping Chung} and Huang, {Shiow Chyn} and Hwang, {Tsong Long} and Chan, {Yu Yi} and Shieh, {Po Chuen} and Ngan, {Nguyen Thi} and Thang, {Tran Dinh} and Wu, {Tian Shung}",
note = "Funding Information: This study was sponsored by the Ministry of Science and Technology, Taiwan, ROC granted to T.-S. Wu, and supported in part by the Vietnam National Foundation for Science and Technology Development (Nr. 104.01-2010.27), and Chang Gung Memorial Hospital (CMRPD1B0481~3, CMRPD1D0281~3, and BMRP450 to H-L Hwang). We also thank Associate Prof. Dr. Tran Huy Thai (Institute of Ecology and Biological Resources, Vietnamese Academy of Science and Technology, Vietnam) for the identification of the plant materials. Publisher Copyright: {\textcopyright} 2016, The Japanese Society of Pharmacognosy and Springer Japan.",
year = "2017",
month = jan,
day = "1",
doi = "10.1007/s11418-016-1033-x",
language = "English",
volume = "71",
pages = "96--104",
journal = "Journal of Natural Medicines",
issn = "1340-3443",
publisher = "Springer Verlag",
number = "1",
}