Constituents from the leaves of Phellodendron amurense and their antioxidant activity

Chien Hsing Leu, Chia Ying Li, Xinsheng Yao, Tian Shung Wu

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Three new coumarins, phellodenols F-H (1-3) and a new glutaric acid derivative, phellodendric acid-A (4) were isolated from the leaves of Phellodendron amurense together with twenty-nine known compounds. Extensive 1D and 2D NMR experiments and other spectroscopic studies were employed to determine the structures of 1-4. The isolated compounds were screened for their antioxidant activity through DPPH (α,α-diphenyl-β- picrylhydrazyl) radical scavenging assay. Compounds quercetin, quercetin-3-O-β-D-glucoside, quercetin-3-O-β-D-galactoside and kaempferol-3-O-β-D-glucoside demonstrated significant radical scavenging activity comparable to vitamin E.

Original languageEnglish
Pages (from-to)1308-1311
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume54
Issue number9
DOIs
Publication statusPublished - 2006

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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