Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu; Tian Shung Wu; Cai Xia He; Chia Hao Su; Kuo Hsiung Lee

doi:10.1248/cpb.53.56

Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu, Tian Shung Wu, Cai Xia He, Chia Hao Su, Kuo Hsiung Lee

School of Pharmacy

Research output: Contribution to journal › Article

36 Citations (Scopus)

Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

Original language	English
Pages (from-to)	56-59
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	53
Issue number	1
DOIs	https://doi.org/10.1248/cpb.53.56
Publication status	Published - 2005 Jan 1

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All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

Cite this

Wu, P. L., Wu, T. S., He, C. X., Su, C. H., & Lee, K. H. (2005). Constituents from the stems of Hibiscus taiwanensis. Chemical and Pharmaceutical Bulletin, 53(1), 56-59. https://doi.org/10.1248/cpb.53.56

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10.1248/cpb.53.56