Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu; Tian Shung Wu; Cai Xia He; Chia Hao Su; Kuo Hsiung Lee

doi:10.1248/cpb.53.56

Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu, Tian Shung Wu, Cai Xia He, Chia Hao Su, Kuo Hsiung Lee

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

Original language	English
Pages (from-to)	56-59
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	53
Issue number	1
DOIs	https://doi.org/10.1248/cpb.53.56
Publication status	Published - 2005 Jan

All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

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title = "Constituents from the stems of Hibiscus taiwanensis",

abstract = "Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.",

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T1 - Constituents from the stems of Hibiscus taiwanensis

AU - Wu, Pei Lin

AU - Wu, Tian Shung

AU - He, Cai Xia

AU - Su, Chia Hao

AU - Lee, Kuo Hsiung

PY - 2005/1

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AB - Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

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