Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu, Tian Shung Wu, Cai Xia He, Chia Hao Su, Kuo Hsiung Lee

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume53
Issue number1
DOIs
Publication statusPublished - 2005 Jan

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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