Constituents of leaves of phellodendron japonicum MAXIM. and their antioxidant activity

Chih Yang Chiu; Chia Ying Li; Chao Chen Chiu; Masatake Niwa; Susumu Kitanaka; Amooru Gangaiah Damu; E. Jian Lee; Tian Shung Wu

doi:10.1248/cpb.53.1118

Constituents of leaves of phellodendron japonicum MAXIM. and their antioxidant activity

Chih Yang Chiu, Chia Ying Li, Chao Chen Chiu, Masatake Niwa, Susumu Kitanaka, Amooru Gangaiah Damu, E. Jian Lee, Tian Shung Wu

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Three new flavonoid derivatives, 6‴-O-acetyl amurensin (1), 6‴-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.

Original language	English
Pages (from-to)	1118-1121
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	53
Issue number	9
DOIs	https://doi.org/10.1248/cpb.53.1118
Publication status	Published - 2005 Sept

All Science Journal Classification (ASJC) codes

General Chemistry
Drug Discovery

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abstract = "Three new flavonoid derivatives, 6‴-O-acetyl amurensin (1), 6‴-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.",

author = "Chiu, {Chih Yang} and Li, {Chia Ying} and Chiu, {Chao Chen} and Masatake Niwa and Susumu Kitanaka and Damu, {Amooru Gangaiah} and Lee, {E. Jian} and Wu, {Tian Shung}",

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AU - Chiu, Chih Yang

AU - Li, Chia Ying

AU - Chiu, Chao Chen

AU - Niwa, Masatake

AU - Kitanaka, Susumu

AU - Damu, Amooru Gangaiah

AU - Lee, E. Jian

AU - Wu, Tian Shung

PY - 2005/9

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AB - Three new flavonoid derivatives, 6‴-O-acetyl amurensin (1), 6‴-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.

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Constituents of leaves of phellodendron japonicum MAXIM. and their antioxidant activity

Abstract

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