Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review

I. Wen Lee, Mei-Tsz Su, Chao Chin Hsu, Ying Hui Lin, Pei Yi Chen, Pao-Lin Kuo

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Complex chromosomal rearrangements are very rare and may lead to spermatogenic defect. We report on an infertile man with complex constitutional chromosomal rearrangements. The chromosomal breakpoints were located at 9p22, 13q22, and 21p11. This is the seventh case, to our knowledge, of complex chromosome rearrangements in a man presenting with a spermatogenic defect. The spermatogenic defect may be ascribed to disruption of sterile genes during chromosomal breakage or abnormal meiotic segregation of the rearranged chromosomes.

Original languageEnglish
Pages (from-to)1343.e5-1343.e8
JournalUrology
Volume68
Issue number6
DOIs
Publication statusPublished - 2006 Jan 1

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Chromosome Breakage
Chromosome Segregation
Chromosomes
Genes

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Lee, I. Wen ; Su, Mei-Tsz ; Hsu, Chao Chin ; Lin, Ying Hui ; Chen, Pei Yi ; Kuo, Pao-Lin. / Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review. In: Urology. 2006 ; Vol. 68, No. 6. pp. 1343.e5-1343.e8.
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Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review. / Lee, I. Wen; Su, Mei-Tsz; Hsu, Chao Chin; Lin, Ying Hui; Chen, Pei Yi; Kuo, Pao-Lin.

In: Urology, Vol. 68, No. 6, 01.01.2006, p. 1343.e5-1343.e8.

Research output: Contribution to journalArticle

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