Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review

I. Wen Lee; Mei Tsz Su; Chao Chin Hsu; Ying Hui Lin; Pei Yi Chen; Pao Lin Kuo

doi:10.1016/j.urology.2006.09.007

Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review

I. Wen Lee, Mei Tsz Su, Chao Chin Hsu, Ying Hui Lin, Pei Yi Chen, Pao Lin Kuo

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Complex chromosomal rearrangements are very rare and may lead to spermatogenic defect. We report on an infertile man with complex constitutional chromosomal rearrangements. The chromosomal breakpoints were located at 9p22, 13q22, and 21p11. This is the seventh case, to our knowledge, of complex chromosome rearrangements in a man presenting with a spermatogenic defect. The spermatogenic defect may be ascribed to disruption of sterile genes during chromosomal breakage or abnormal meiotic segregation of the rearranged chromosomes.

Original language	English
Pages (from-to)	1343.e5-1343.e8
Journal	Urology
Volume	68
Issue number	6
DOIs	https://doi.org/10.1016/j.urology.2006.09.007
Publication status	Published - 2006 Dec

All Science Journal Classification (ASJC) codes

Urology

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10.1016/j.urology.2006.09.007

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title = "Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review",

abstract = "Complex chromosomal rearrangements are very rare and may lead to spermatogenic defect. We report on an infertile man with complex constitutional chromosomal rearrangements. The chromosomal breakpoints were located at 9p22, 13q22, and 21p11. This is the seventh case, to our knowledge, of complex chromosome rearrangements in a man presenting with a spermatogenic defect. The spermatogenic defect may be ascribed to disruption of sterile genes during chromosomal breakage or abnormal meiotic segregation of the rearranged chromosomes.",

author = "Lee, {I. Wen} and Su, {Mei Tsz} and Hsu, {Chao Chin} and Lin, {Ying Hui} and Chen, {Pei Yi} and Kuo, {Pao Lin}",

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AU - Su, Mei Tsz

AU - Hsu, Chao Chin

AU - Lin, Ying Hui

AU - Chen, Pei Yi

AU - Kuo, Pao Lin

PY - 2006/12

Y1 - 2006/12

N2 - Complex chromosomal rearrangements are very rare and may lead to spermatogenic defect. We report on an infertile man with complex constitutional chromosomal rearrangements. The chromosomal breakpoints were located at 9p22, 13q22, and 21p11. This is the seventh case, to our knowledge, of complex chromosome rearrangements in a man presenting with a spermatogenic defect. The spermatogenic defect may be ascribed to disruption of sterile genes during chromosomal breakage or abnormal meiotic segregation of the rearranged chromosomes.

AB - Complex chromosomal rearrangements are very rare and may lead to spermatogenic defect. We report on an infertile man with complex constitutional chromosomal rearrangements. The chromosomal breakpoints were located at 9p22, 13q22, and 21p11. This is the seventh case, to our knowledge, of complex chromosome rearrangements in a man presenting with a spermatogenic defect. The spermatogenic defect may be ascribed to disruption of sterile genes during chromosomal breakage or abnormal meiotic segregation of the rearranged chromosomes.

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JO - Urology

JF - Urology

IS - 6

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Constitutional complex chromosomal rearrangements in azoospermic men-case report and literature review

Abstract

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