Continuous particle sorting utilizing cascade squeeze-jumping effect under microfluidic configuration

Che Hsin Lin, Cheng Yan Lee, Lung-Ming Fu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper presents a novel method for continuous particle sorting and collection by using of cascade squeeze-jumping effect under microfluidic configuration. Microparticles with different sizes can be successfully separated at different stages of squeezed sheath flows. Separated microparticles then flow into expansion channel blocks to enlarge the distance of the separated flow streams and are collected at different side channels. Only one high voltage is required for generating all the sheath flows for particle separation by applying a series of variable resister to create different electric field levels such that the system is simple and reliable. This study also adopts numerical simulation to analyze and predict the flow fields and stream lines within the microchannel. Experimental results show that the microchip is capable of continuously separating microparticles with the sizes of 5, 10 and 20 μm using the proposed squeeze-jumping effect. The method proposed in this study provides a simple way to continuously separate microparticles/cells with different sizes. More importantly, no delicate control system and fabrication process are required to achieve the sorting and collection.

Original languageEnglish
Title of host publication19th IEEE International Conference on Micro Electro Mechanical Systems
Pages206-209
Number of pages4
Publication statusPublished - 2006 Oct 24
Event19th IEEE International Conference on Micro Electro Mechanical Systems - Istanbul, Turkey
Duration: 2006 Jan 222006 Jan 26

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2006
ISSN (Print)1084-6999

Other

Other19th IEEE International Conference on Micro Electro Mechanical Systems
CountryTurkey
CityIstanbul
Period06-01-2206-01-26

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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