Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Chaitanya Kurhade, Sarah Schreier, Yi Ping Lee, Loreen Zegenhagen, Marika Hjertqvist, Gerhard Dobler, Andrea Kröger, Anna K. Överby

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2 Citations (Scopus)

Abstract

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

Original languageEnglish
Pages (from-to)1709-1712
Number of pages4
JournalEmerging infectious diseases
Volume24
Issue number9
DOIs
Publication statusPublished - 2018 Sep

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All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Kurhade, C., Schreier, S., Lee, Y. P., Zegenhagen, L., Hjertqvist, M., Dobler, G., Kröger, A., & Överby, A. K. (2018). Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice. Emerging infectious diseases, 24(9), 1709-1712. https://doi.org/10.3201/eid2409.171825