Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))

Hsuan Yu Lai; Ko Hua Yu; Keng Chang Tsai; Chao Chang Lee; Han Yu Wang; Yi Ping Hsieh; Kuan Yi Chiang; Pao Lin Kuo; Tze Ta Huang; Hsin Yi Hung

doi:10.1016/j.bioorg.2024.108100

Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))

Hsuan Yu Lai, Ko Hua Yu, Keng Chang Tsai, Chao Chang Lee, Han Yu Wang, Yi Ping Hsieh, Kuan Yi Chiang, Pao Lin Kuo, Tze Ta Huang, Hsin Yi Hung

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Highlight • Twenty-three forchlorfenuron derivatives were evaluated for SEPT9 inhibition.• 6b, 8a, and 8b are SEPT9 inhibitors with IC₅₀ values of 90, 99, and 94 μM, respectively.• Marked suppression of the cell migration and the invasion ability was observed with 8b treatment.• 8b effectively disrupted the structural organization of SEPT9, microtubules, and actins.

Original language	English
Article number	108100
Journal	Bioorganic Chemistry
Volume	154
DOIs	https://doi.org/10.1016/j.bioorg.2024.108100
Publication status	Published - 2025 Jan

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Drug Discovery
Organic Chemistry

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10.1016/j.bioorg.2024.108100

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Lai, H. Y., Yu, K. H., Tsai, K. C., Lee, C. C., Wang, H. Y., Hsieh, Y. P., Chiang, K. Y., Kuo, P. L., Huang, T. T., & Hung, H. Y. (2025). Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068)). Bioorganic Chemistry, 154, Article 108100. https://doi.org/10.1016/j.bioorg.2024.108100

@article{13973da7f9f840e18dae725f07ad0f1a,

title = "Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))",

abstract = "Highlight • Twenty-three forchlorfenuron derivatives were evaluated for SEPT9 inhibition.• 6b, 8a, and 8b are SEPT9 inhibitors with IC50 values of 90, 99, and 94 μM, respectively.• Marked suppression of the cell migration and the invasion ability was observed with 8b treatment.• 8b effectively disrupted the structural organization of SEPT9, microtubules, and actins.",

author = "Lai, {Hsuan Yu} and Yu, {Ko Hua} and Tsai, {Keng Chang} and Lee, {Chao Chang} and Wang, {Han Yu} and Hsieh, {Yi Ping} and Chiang, {Kuan Yi} and Kuo, {Pao Lin} and Huang, {Tze Ta} and Hung, {Hsin Yi}",

note = "Publisher Copyright: {\textcopyright} 2024",

year = "2025",

month = jan,

doi = "10.1016/j.bioorg.2024.108100",

language = "English",

volume = "154",

journal = "Bioorganic Chemistry",

issn = "0045-2068",

publisher = "Academic Press Inc.",

}

Lai, HY, Yu, KH, Tsai, KC, Lee, CC, Wang, HY, Hsieh, YP, Chiang, KY, Kuo, PL , Huang, TT & Hung, HY 2025, 'Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))', Bioorganic Chemistry, vol. 154, 108100. https://doi.org/10.1016/j.bioorg.2024.108100

Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068)). / Lai, Hsuan Yu; Yu, Ko Hua; Tsai, Keng Chang et al.
In: Bioorganic Chemistry, Vol. 154, 108100, 01.2025.

Research output: Contribution to journal › Comment/debate › peer-review

TY - JOUR

T1 - Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))

AU - Lai, Hsuan Yu

AU - Yu, Ko Hua

AU - Tsai, Keng Chang

AU - Lee, Chao Chang

AU - Wang, Han Yu

AU - Hsieh, Yi Ping

AU - Chiang, Kuan Yi

AU - Kuo, Pao Lin

AU - Huang, Tze Ta

AU - Hung, Hsin Yi

PY - 2025/1

Y1 - 2025/1

N2 - Highlight • Twenty-three forchlorfenuron derivatives were evaluated for SEPT9 inhibition.• 6b, 8a, and 8b are SEPT9 inhibitors with IC50 values of 90, 99, and 94 μM, respectively.• Marked suppression of the cell migration and the invasion ability was observed with 8b treatment.• 8b effectively disrupted the structural organization of SEPT9, microtubules, and actins.

AB - Highlight • Twenty-three forchlorfenuron derivatives were evaluated for SEPT9 inhibition.• 6b, 8a, and 8b are SEPT9 inhibitors with IC50 values of 90, 99, and 94 μM, respectively.• Marked suppression of the cell migration and the invasion ability was observed with 8b treatment.• 8b effectively disrupted the structural organization of SEPT9, microtubules, and actins.

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U2 - 10.1016/j.bioorg.2024.108100

DO - 10.1016/j.bioorg.2024.108100

M3 - Comment/debate

C2 - 39741018

AN - SCOPUS:85214200067

SN - 0045-2068

VL - 154

JO - Bioorganic Chemistry

JF - Bioorganic Chemistry

M1 - 108100

ER -

Lai HY, Yu KH, Tsai KC, Lee CC, Wang HY, Hsieh YP et al. Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068)). Bioorganic Chemistry. 2025 Jan;154:108100. doi: 10.1016/j.bioorg.2024.108100

Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] (Bioorganic Chemistry (2025) 154, (S0045206824009738), (10.1016/j.bioorg.2024.108068))

Abstract

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