Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index

Yuan Lin Liao, Yung Nien Sun, Jen Chuen Hsieh, Tung Ping Su, Wan Yuo Guo, Yu Te Wu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Bipolar disorder (BD) is a common affective disorder. In morphometric brain imaging studies, BD subjects have atrophic gray matter, especially in the prefrontal area. These structural abnormalities could involve the change of cortical shape. Gyrification index (GI) is a useful metric to measure the degree of cortical complexity. This work aims to compare the cortical development between bipolar patients and healthy controls using GI. No significant difference was detected between two groups. However, we found asymmetry pattern of cortical complexity was increased in limbic lobe on bipolar patients. Significant negative correlation was also observed between rating scores and asymmetry coefficients in frontal lobe.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages3933-3936
Number of pages4
Publication statusPublished - 2008 Dec 1
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 2008 Aug 202008 Aug 25

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period08-08-2008-08-25

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Fingerprint Dive into the research topics of 'Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index'. Together they form a unique fingerprint.

  • Cite this

    Liao, Y. L., Sun, Y. N., Hsieh, J. C., Su, T. P., Guo, W. Y., & Wu, Y. T. (2008). Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 3933-3936). [4650070] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").