Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index

Yuan Lin Liao; Yung Nien Sun; Jen Chuen Hsieh; Tung Ping Su; Wan Yuo Guo; Yu Te Wu

Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index

Yuan Lin Liao, Yung Nien Sun, Jen Chuen Hsieh, Tung Ping Su, Wan Yuo Guo, Yu Te Wu

Department of Computer Science and Information Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

Bipolar disorder (BD) is a common affective disorder. In morphometric brain imaging studies, BD subjects have atrophic gray matter, especially in the prefrontal area. These structural abnormalities could involve the change of cortical shape. Gyrification index (GI) is a useful metric to measure the degree of cortical complexity. This work aims to compare the cortical development between bipolar patients and healthy controls using GI. No significant difference was detected between two groups. However, we found asymmetry pattern of cortical complexity was increased in limbic lobe on bipolar patients. Significant negative correlation was also observed between rating scores and asymmetry coefficients in frontal lobe.

Original language	English
Title of host publication	Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages	3933-3936
Number of pages	4
Publication status	Published - 2008 Dec 1
Event	30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada Duration: 2008 Aug 20 → 2008 Aug 25

Publication series

Name	Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other	30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Country	Canada
City	Vancouver, BC
Period	08-08-20 → 08-08-25

All Science Journal Classification (ASJC) codes

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

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Liao, Y. L., Sun, Y. N., Hsieh, J. C., Su, T. P., Guo, W. Y., & Wu, Y. T. (2008). Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 3933-3936). [4650070] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

Liao, Yuan Lin ; Sun, Yung Nien ; Hsieh, Jen Chuen ; Su, Tung Ping ; Guo, Wan Yuo ; Wu, Yu Te. / Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. pp. 3933-3936 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

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title = "Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index",

abstract = "Bipolar disorder (BD) is a common affective disorder. In morphometric brain imaging studies, BD subjects have atrophic gray matter, especially in the prefrontal area. These structural abnormalities could involve the change of cortical shape. Gyrification index (GI) is a useful metric to measure the degree of cortical complexity. This work aims to compare the cortical development between bipolar patients and healthy controls using GI. No significant difference was detected between two groups. However, we found asymmetry pattern of cortical complexity was increased in limbic lobe on bipolar patients. Significant negative correlation was also observed between rating scores and asymmetry coefficients in frontal lobe.",

author = "Liao, {Yuan Lin} and Sun, {Yung Nien} and Hsieh, {Jen Chuen} and Su, {Tung Ping} and Guo, {Wan Yuo} and Wu, {Yu Te}",

year = "2008",

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booktitle = "Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08",

note = "30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 ; Conference date: 20-08-2008 Through 25-08-2008",

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Liao, YL, Sun, YN, Hsieh, JC, Su, TP, Guo, WY & Wu, YT 2008, Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08., 4650070, Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology", pp. 3933-3936, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 08-08-20.

Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. / Liao, Yuan Lin; Sun, Yung Nien; Hsieh, Jen Chuen; Su, Tung Ping; Guo, Wan Yuo; Wu, Yu Te.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 3933-3936 4650070 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Wu, Yu Te

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AB - Bipolar disorder (BD) is a common affective disorder. In morphometric brain imaging studies, BD subjects have atrophic gray matter, especially in the prefrontal area. These structural abnormalities could involve the change of cortical shape. Gyrification index (GI) is a useful metric to measure the degree of cortical complexity. This work aims to compare the cortical development between bipolar patients and healthy controls using GI. No significant difference was detected between two groups. However, we found asymmetry pattern of cortical complexity was increased in limbic lobe on bipolar patients. Significant negative correlation was also observed between rating scores and asymmetry coefficients in frontal lobe.

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Liao YL, Sun YN, Hsieh JC, Su TP, Guo WY, Wu YT. Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 3933-3936. 4650070. (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").