Cryptococcus neoformans peritonitis in two patients with liver cirrhosis

Shio Shin Jean, Jiun-Ling Wang, Jann Tay Wang, Chi Tai Fang, Yee Chun Chen, Shan Chwen Chang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cryptococcus neoformans is an important pathogen in immunocompromised patients. We report 2 cases of spontaneous C. neoformans peritonitis in patients with liver cirrhosis, a condition not previously reported in Taiwan. Patient 1, a 59-year-old man with alcoholic liver cirrhosis, had primary C. neoformans peritonitis with fungemia. The patient recovered completely after prolonged fluconazole therapy without relapse. Patient 2, a 51-year-old woman with liver cirrhosis due to Budd-Chiari syndrome, had C. neoformans isolated from ascites, cerebrospinal fluid, and blood culture. In spite of adequate antifungal treatment, the patient died of fulminant sepsis. Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalJournal of the Formosan Medical Association
Volume104
Issue number1
Publication statusPublished - 2005 Dec 1

Fingerprint

Cryptococcus neoformans
Peritonitis
Liver Cirrhosis
Fungemia
Budd-Chiari Syndrome
Alcoholic Liver Cirrhosis
Fluconazole
Immunocompromised Host
Taiwan
Ascites
Cerebrospinal Fluid
Sepsis
Therapeutics
Recurrence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Jean, S. S., Wang, J-L., Wang, J. T., Fang, C. T., Chen, Y. C., & Chang, S. C. (2005). Cryptococcus neoformans peritonitis in two patients with liver cirrhosis. Journal of the Formosan Medical Association, 104(1), 39-42.
Jean, Shio Shin ; Wang, Jiun-Ling ; Wang, Jann Tay ; Fang, Chi Tai ; Chen, Yee Chun ; Chang, Shan Chwen. / Cryptococcus neoformans peritonitis in two patients with liver cirrhosis. In: Journal of the Formosan Medical Association. 2005 ; Vol. 104, No. 1. pp. 39-42.
@article{b94a3a90cd014ac9be26d785c53a796e,
title = "Cryptococcus neoformans peritonitis in two patients with liver cirrhosis",
abstract = "Cryptococcus neoformans is an important pathogen in immunocompromised patients. We report 2 cases of spontaneous C. neoformans peritonitis in patients with liver cirrhosis, a condition not previously reported in Taiwan. Patient 1, a 59-year-old man with alcoholic liver cirrhosis, had primary C. neoformans peritonitis with fungemia. The patient recovered completely after prolonged fluconazole therapy without relapse. Patient 2, a 51-year-old woman with liver cirrhosis due to Budd-Chiari syndrome, had C. neoformans isolated from ascites, cerebrospinal fluid, and blood culture. In spite of adequate antifungal treatment, the patient died of fulminant sepsis. Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis.",
author = "Jean, {Shio Shin} and Jiun-Ling Wang and Wang, {Jann Tay} and Fang, {Chi Tai} and Chen, {Yee Chun} and Chang, {Shan Chwen}",
year = "2005",
month = "12",
day = "1",
language = "English",
volume = "104",
pages = "39--42",
journal = "Journal of the Formosan Medical Association",
issn = "0929-6646",
publisher = "Excerpta Medica Asia Ltd.",
number = "1",

}

Jean, SS, Wang, J-L, Wang, JT, Fang, CT, Chen, YC & Chang, SC 2005, 'Cryptococcus neoformans peritonitis in two patients with liver cirrhosis', Journal of the Formosan Medical Association, vol. 104, no. 1, pp. 39-42.

Cryptococcus neoformans peritonitis in two patients with liver cirrhosis. / Jean, Shio Shin; Wang, Jiun-Ling; Wang, Jann Tay; Fang, Chi Tai; Chen, Yee Chun; Chang, Shan Chwen.

In: Journal of the Formosan Medical Association, Vol. 104, No. 1, 01.12.2005, p. 39-42.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cryptococcus neoformans peritonitis in two patients with liver cirrhosis

AU - Jean, Shio Shin

AU - Wang, Jiun-Ling

AU - Wang, Jann Tay

AU - Fang, Chi Tai

AU - Chen, Yee Chun

AU - Chang, Shan Chwen

PY - 2005/12/1

Y1 - 2005/12/1

N2 - Cryptococcus neoformans is an important pathogen in immunocompromised patients. We report 2 cases of spontaneous C. neoformans peritonitis in patients with liver cirrhosis, a condition not previously reported in Taiwan. Patient 1, a 59-year-old man with alcoholic liver cirrhosis, had primary C. neoformans peritonitis with fungemia. The patient recovered completely after prolonged fluconazole therapy without relapse. Patient 2, a 51-year-old woman with liver cirrhosis due to Budd-Chiari syndrome, had C. neoformans isolated from ascites, cerebrospinal fluid, and blood culture. In spite of adequate antifungal treatment, the patient died of fulminant sepsis. Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis.

AB - Cryptococcus neoformans is an important pathogen in immunocompromised patients. We report 2 cases of spontaneous C. neoformans peritonitis in patients with liver cirrhosis, a condition not previously reported in Taiwan. Patient 1, a 59-year-old man with alcoholic liver cirrhosis, had primary C. neoformans peritonitis with fungemia. The patient recovered completely after prolonged fluconazole therapy without relapse. Patient 2, a 51-year-old woman with liver cirrhosis due to Budd-Chiari syndrome, had C. neoformans isolated from ascites, cerebrospinal fluid, and blood culture. In spite of adequate antifungal treatment, the patient died of fulminant sepsis. Information about the interaction and relation between liver cirrhosis and cryptococcal peritonitis is rare in the literature. The experience of these cases may help facilitate the diagnosis and treatment of cryptococcal peritonitis.

UR - http://www.scopus.com/inward/record.url?scp=14544308949&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=14544308949&partnerID=8YFLogxK

M3 - Article

VL - 104

SP - 39

EP - 42

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

SN - 0929-6646

IS - 1

ER -