Cytotoxic arylnaphthalene lignans from Phyllanthus oligospermus

Shwu Jen Wu, Tian Shung Wu

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Three new arylnaphthalene lignans, namely phyllanthusmins A-C, together with nine known compounds were isolated and characterized from the stems and roots of Phyllanthus oligospermus by a bioassay-guided purification. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Among them, phyllanthusminA displayed significant cytotoxicity against KB and P-388 cancer cell lines.

Original languageEnglish
Pages (from-to)1223-1225
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume54
Issue number8
DOIs
Publication statusPublished - 2006

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Drug Discovery

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