Cytotoxic principles from the leaves of Tithonia diversifolia

Tian Shung Wu; Li Shian Shi; Ping Chung Kuo; Yann Lii Leu; Meei Jen Liou; Pei Lin Wu; Yang Chang Wu; Song Chou Iou; Yuh Pan Chen; Hsien Chang Chang

Cytotoxic principles from the leaves of Tithonia diversifolia

Tian Shung Wu
, Li Shian Shi
, Ping Chung Kuo
, Yann Lii Leu
, Meei Jen Liou
, Pei Lin Wu
, Yang Chang Wu
, Song Chou Iou
, Yuh Pan Chen
, Hsien Chang Chang

Research output: Contribution to journal › Article › peer-review

Abstract

Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

Original language	English
Pages (from-to)	217-223
Number of pages	7
Journal	Chinese Pharmaceutical Journal
Volume	53
Issue number	5
Publication status	Published - 2001

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science

Cite this

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title = "Cytotoxic principles from the leaves of Tithonia diversifolia",

abstract = "Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.",

author = "Wu, \{Tian Shung\} and Shi, \{Li Shian\} and Kuo, \{Ping Chung\} and Leu, \{Yann Lii\} and Liou, \{Meei Jen\} and Wu, \{Pei Lin\} and Wu, \{Yang Chang\} and Iou, \{Song Chou\} and Chen, \{Yuh Pan\} and Chang, \{Hsien Chang\}",

year = "2001",

language = "English",

volume = "53",

pages = "217--223",

journal = "Chinese Pharmaceutical Journal",

issn = "1016-1015",

publisher = "Pharmaceutical Society of Republic of China",

number = "5",

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TY - JOUR

T1 - Cytotoxic principles from the leaves of Tithonia diversifolia

AU - Wu, Tian Shung

AU - Shi, Li Shian

AU - Kuo, Ping Chung

AU - Leu, Yann Lii

AU - Liou, Meei Jen

AU - Wu, Pei Lin

AU - Wu, Yang Chang

AU - Iou, Song Chou

AU - Chen, Yuh Pan

AU - Chang, Hsien Chang

PY - 2001

Y1 - 2001

N2 - Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

AB - Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

UR - https://www.scopus.com/pages/publications/0035713797

UR - https://www.scopus.com/pages/publications/0035713797#tab=citedBy

M3 - Article

AN - SCOPUS:0035713797

SN - 1016-1015

VL - 53

SP - 217

EP - 223

JO - Chinese Pharmaceutical Journal

JF - Chinese Pharmaceutical Journal

IS - 5

ER -

Cytotoxic principles from the leaves of Tithonia diversifolia

Abstract

All Science Journal Classification (ASJC) codes

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