Cytotoxicity of Ganoderma lucidum triterpenes

Tian-Shung Wu, L. S. Shi, S. C. Kuo

Research output: Contribution to journalArticlepeer-review

137 Citations (Scopus)


Two new triterpenoids, lucidenic acid N (1) and methyl lucidenate F (2), together with four known compounds, lucidenic acid A, lucidenolactone, lucidenic acid C, and ganoderic acid E, were isolated from the dried fruiting bodies of Ganoderma lucidum. Their structures were elucidated by spectral and chemical transformation studies. Among them, lucidenic acid N (1), lucidenic acid A, and ganoderic acid E showed significant cytotoxic activity against Hep G2, Hep G2,2,15, and P-388 tumor cells.

Original languageEnglish
Pages (from-to)1121-1122
Number of pages2
JournalJournal of Natural Products
Issue number8
Publication statusPublished - 2001 Sept 11

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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