Daily life events influence the results of the dexamethasone suppression test in healthy women

Wei Tseng Chen, Tzung Lieh Yeh, Venla Lehti, Shu Hui Cheng, Ching Lin Chu, Kao Chin Chen, I. Hui Lee, Po See Chen, Yen Kuang Yang

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Although the Dexamethasone Suppression Test (DST) plays an important role in psychosomatic research, confounding factors limit the sensitivity and specificity of the DST. The aim of this study was to investigate the relationship between the intensity of daily life stressors and DST results in healthy participants after controlling the confounding factors. The subjects of this study consisted of 75 healthy volunteers. The intensity of daily life events was assessed using the Taiwanese version of the Recent Life Change Questionnaire (RLCQ). Neuroticism was assessed using the Maudsley Personality Inventory (MPI). The Dexamethasone Suppression Test (DST) was also performed. The regression model showed that daily life events (RLCQ score) were correlated significantly with cortisol level on day 1 and D% only in women. This finding implies that daily life events should be considered as an independent variable in women in further studies when the DST is applied.

Original languageEnglish
Pages (from-to)49-53
Number of pages5
JournalBehavioral Medicine
Volume38
Issue number2
DOIs
Publication statusPublished - 2012 Apr 1

All Science Journal Classification (ASJC) codes

  • Applied Psychology
  • Psychiatry and Mental health

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