Dental implant failure associated with bacterial infection and long-term bisphosphonate usage: A case report

Kuo Yuan, Ken Chung Chen, Ying Jen Chan, Chun Chun Tsai, Hui Hwa Chen, Chien Chi Shih

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Although the risk of developing osteonecrosis of the jaw for oral implants in patients using oral bisphosphonates (BPs) is low, the devastating complications still require caution. We document a case of severe periimplant infection that developed after the patient had used oral BPs for 3 years. Exposed bone and osteonecrosis persisted for more than 2 months after 1 infected implant was explanted by a dentist unaware that the patient was taking BPs. After oral BPs had been stopped, another involved implant was explanted, sequestra were removed, a primary closure was sutured, and the antibiotic was changed; then the wound was finally under control. The explanted implant with attached bone was processed for undecalcified ground sections, and specimens from the bony lesion were sent to pathology for examination. Osteonecrosis, severe inflammatory osteolysis, and heavy bacterial colonization were found. Patients at risk must be alerted about the potential risks of implant failure and developing BP-related osteonecrosis of the jaw.

Original languageEnglish
Pages (from-to)3-7
Number of pages5
JournalImplant Dentistry
Volume21
Issue number1
DOIs
Publication statusPublished - 2012 Feb

All Science Journal Classification (ASJC) codes

  • Oral Surgery

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