Dependence of seed layer thickness on sensitivity of nano-ZnO cholesterol biosensor

Yang Ming Lu, Po Chin Wang, Jian Fu Tang, Sheng Yuan Chu

Research output: Contribution to journalConference articlepeer-review

5 Citations (Scopus)


The anemone-like ZnO nanostructures have been synthesized by hydrothermal method and were further adsorbed immobilized cholesterol oxidase (ChOx) as a nano-biosensor. In this study, the sensitivity of biosensor were improved by varying the thickness of the ZnO seed layer. The SEM analysis showed changes in thickness of seed layer will not affect the morphologies of anemone-like ZnO nanostructures. The X-ray Diffraction patterns showed that the (002) plane of anemone-like ZnO grown on various thickness of the seed layer was more prouded than other crystal plane. Abioelectrode (ChOx/ZnO/ITO/glass) grown on the 30nm of ZnO seed layer with high sensitivity of 57.533μAmM-1cm-2 (1.488 μA (mg/dl) -1cm-2), a wide sensitive range from 25 to 500 mg/dl. It is concluded that the thinner sputtered ZnO seed layer for growing anemone-like ZnO nanostructure can effectively improve the sensitivity of the ZnO biosensor.

Original languageEnglish
Article number012021
JournalIOP Conference Series: Materials Science and Engineering
Issue number1
Publication statusPublished - 2017 Feb 13
Event1st International Conference on New Material and Chemical Industry, NMCI 2016 - Sanya, China
Duration: 2016 Nov 192016 Nov 21

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • General Engineering


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