@article{95cdceb7e9d34ceeb5dc549f4b46279f,
title = "Design and synthesis of malonamide derivatives as antibiotics against methicillin-resistant staphylococcus aureus",
abstract = "Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to humans. Most existing antimicrobial drugs, including the β-lactam and quinoxiline classes, are not effective against MRSA. In this study, we synthesized 24 derivatives of malonamide, a new class of antibacterial agents and potentiators of classic antimicrobials. A derivative that increases bacterial killing and biofilm eradication with low cell toxicity was created.",
author = "Su, {Jung Chen} and Huang, {Yu Ting} and Chen, {Chang Shi} and Chiu, {Hao Chieh} and Shiau, {Chung Wai}",
note = "Funding Information: This work was supported by grants from the Ministry of Science and Technology, Taiwan (MOST 104-3113-B-076-001, MOST 104-2321-B-010-017, MOST105-2321-B-010-008, MOST105-2325-B-010-007, MOST 106-2321-B-010-005, MOST106-3011-B-010-001, MOST 106-2320-B-010-018) and the Ministry of Education, Aiming for the Top University Plan (106AC-P645, 106AC-P632, 105AC-P645, 104AC-P693). Funding Information: Acknowledgments: This work was supported by grants from the Ministry of Science and Technology, Taiwan (MOST 104-3113-B-076-001, MOST 104-2321-B-010-017, MOST105-2321-B-010-008, MOST105-2325-B-010-007, MOST 106-2321-B-010-005, MOST106-3011-B-010-001, MOST 106-2320-B-010-018) and the Ministry of Education, Aiming for the Top University Plan (106AC-P645, 106AC-P632, 105AC-P645, 104AC-P693). Publisher Copyright: {\textcopyright} 2017 by the authors.",
year = "2018",
doi = "10.3390/molecules23010027",
language = "English",
volume = "23",
journal = "Molecules",
issn = "1420-3049",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "1",
}