A micro-dosing system of overall size 5×5×4.2 mm3 for drug delivery is proposed and presented. The drug delivery system mainly consists of a micro-wheel and a micro-drug release mechanism. The motion of the micro-wheel is controlled by its center of gravity via a running disk, which is placed within the hollow micro-wheel and attracted by the actuated micro-solenoids fabricated on the inner wall of micro-wheel in shift. In addition, the micro-wheel is controlled to roll forwards/backwards to the designated location by two sliding mode control strategies: one for long-distance motion (to transport the drug to the vicinity of the spots under disease) and the other for short-distance motion (to decelerate down and stop at the exact drug-release location). On the other hand, the microdrug release mechanism is composed by a cantilever beam and a chamber filled up by medicine. The pyramid tip of the cantilever beam deflected by the applied electrostatic force is designed to penetrate the micro-film which seals the chamber so that the medicine can be released at the specified spot.
|Number of pages||11|
|Journal||International Journal of Precision Engineering and Manufacturing|
|Publication status||Published - 2014 Jul|
All Science Journal Classification (ASJC) codes
- Mechanical Engineering
- Industrial and Manufacturing Engineering
- Electrical and Electronic Engineering