Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

Wing Kam Liu, Ashfaq Adnan, Adrian M. Kopacz, Michelle Hallikainen, Dean Ho, Robert Lam, Jessica Lee, Ted Belytschko, George Schatz, Yon-Hua Tzeng, Young Jin Kim, Seunghyun Baik, Moon Ki Kim, Taesung Kim, Junghoon Lee, Eung Soo Hwang, Seyoung Im, Eiji Osawa, Amanda Barnard, Huan Cheng ChangChia Ching Chang, Eugenio Oñate

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Abstract

The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

Original languageEnglish
Title of host publicationNanodiamonds
Subtitle of host publicationApplications in Biology and Nanoscale Medicine
PublisherSpringer US
Pages249-284
Number of pages36
ISBN (Print)9781441905307
DOIs
Publication statusPublished - 2010 Dec 1

Fingerprint

Nanodiamonds
Drug delivery
Cells
Imaging techniques
Tumors
Chemotherapy

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Liu, W. K., Adnan, A., Kopacz, A. M., Hallikainen, M., Ho, D., Lam, R., ... Oñate, E. (2010). Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. In Nanodiamonds: Applications in Biology and Nanoscale Medicine (pp. 249-284). Springer US. https://doi.org/10.1007/978-1-4419-0531-4_12
Liu, Wing Kam ; Adnan, Ashfaq ; Kopacz, Adrian M. ; Hallikainen, Michelle ; Ho, Dean ; Lam, Robert ; Lee, Jessica ; Belytschko, Ted ; Schatz, George ; Tzeng, Yon-Hua ; Kim, Young Jin ; Baik, Seunghyun ; Kim, Moon Ki ; Kim, Taesung ; Lee, Junghoon ; Hwang, Eung Soo ; Im, Seyoung ; Osawa, Eiji ; Barnard, Amanda ; Chang, Huan Cheng ; Chang, Chia Ching ; Oñate, Eugenio. / Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. Nanodiamonds: Applications in Biology and Nanoscale Medicine. Springer US, 2010. pp. 249-284
@inbook{b52dd2014fdf48acbc41b81da15408c4,
title = "Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications",
abstract = "The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.",
author = "Liu, {Wing Kam} and Ashfaq Adnan and Kopacz, {Adrian M.} and Michelle Hallikainen and Dean Ho and Robert Lam and Jessica Lee and Ted Belytschko and George Schatz and Yon-Hua Tzeng and Kim, {Young Jin} and Seunghyun Baik and Kim, {Moon Ki} and Taesung Kim and Junghoon Lee and Hwang, {Eung Soo} and Seyoung Im and Eiji Osawa and Amanda Barnard and Chang, {Huan Cheng} and Chang, {Chia Ching} and Eugenio O{\~n}ate",
year = "2010",
month = "12",
day = "1",
doi = "10.1007/978-1-4419-0531-4_12",
language = "English",
isbn = "9781441905307",
pages = "249--284",
booktitle = "Nanodiamonds",
publisher = "Springer US",
address = "United States",

}

Liu, WK, Adnan, A, Kopacz, AM, Hallikainen, M, Ho, D, Lam, R, Lee, J, Belytschko, T, Schatz, G, Tzeng, Y-H, Kim, YJ, Baik, S, Kim, MK, Kim, T, Lee, J, Hwang, ES, Im, S, Osawa, E, Barnard, A, Chang, HC, Chang, CC & Oñate, E 2010, Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. in Nanodiamonds: Applications in Biology and Nanoscale Medicine. Springer US, pp. 249-284. https://doi.org/10.1007/978-1-4419-0531-4_12

Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. / Liu, Wing Kam; Adnan, Ashfaq; Kopacz, Adrian M.; Hallikainen, Michelle; Ho, Dean; Lam, Robert; Lee, Jessica; Belytschko, Ted; Schatz, George; Tzeng, Yon-Hua; Kim, Young Jin; Baik, Seunghyun; Kim, Moon Ki; Kim, Taesung; Lee, Junghoon; Hwang, Eung Soo; Im, Seyoung; Osawa, Eiji; Barnard, Amanda; Chang, Huan Cheng; Chang, Chia Ching; Oñate, Eugenio.

Nanodiamonds: Applications in Biology and Nanoscale Medicine. Springer US, 2010. p. 249-284.

Research output: Chapter in Book/Report/Conference proceedingChapter

TY - CHAP

T1 - Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

AU - Liu, Wing Kam

AU - Adnan, Ashfaq

AU - Kopacz, Adrian M.

AU - Hallikainen, Michelle

AU - Ho, Dean

AU - Lam, Robert

AU - Lee, Jessica

AU - Belytschko, Ted

AU - Schatz, George

AU - Tzeng, Yon-Hua

AU - Kim, Young Jin

AU - Baik, Seunghyun

AU - Kim, Moon Ki

AU - Kim, Taesung

AU - Lee, Junghoon

AU - Hwang, Eung Soo

AU - Im, Seyoung

AU - Osawa, Eiji

AU - Barnard, Amanda

AU - Chang, Huan Cheng

AU - Chang, Chia Ching

AU - Oñate, Eugenio

PY - 2010/12/1

Y1 - 2010/12/1

N2 - The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

AB - The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

UR - http://www.scopus.com/inward/record.url?scp=84861662465&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861662465&partnerID=8YFLogxK

U2 - 10.1007/978-1-4419-0531-4_12

DO - 10.1007/978-1-4419-0531-4_12

M3 - Chapter

AN - SCOPUS:84861662465

SN - 9781441905307

SP - 249

EP - 284

BT - Nanodiamonds

PB - Springer US

ER -

Liu WK, Adnan A, Kopacz AM, Hallikainen M, Ho D, Lam R et al. Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. In Nanodiamonds: Applications in Biology and Nanoscale Medicine. Springer US. 2010. p. 249-284 https://doi.org/10.1007/978-1-4419-0531-4_12