Detection methods and applications of microfluidic paper-based analytical devices

Lung Ming Fu, Yao Nan Wang

Research output: Contribution to journalReview articlepeer-review

193 Citations (Scopus)


This review reports on recent advances in state-of-the-art detection methods for microfluidic paper-based analytical devices (μPADs). The review commences by describing the materials, fabrication methods and driving mechanisms employed in μPADs. The review then explores the main detection methods and applications of μPADs proposed over the past five years. The discussions focus on seven detection technologies, namely (1) colorimetric detection, (2) fluorescent detection, (3) electrochemical detection and photoelectrochemical detection, (4) chemiluminescent detection, (5) electrochemiluminescent detection, (6) nanoparticle-based detection, and (7) spectrometry detection. Overall, the review provides a useful insight into recent advances in the μPAD detection field and serves as a useful source of reference for further research and innovation in the field.

Original languageEnglish
Pages (from-to)196-211
Number of pages16
JournalTrAC - Trends in Analytical Chemistry
Publication statusPublished - 2018 Oct

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Spectroscopy

Cite this