Detection of uric acid based on multi-walled carbon nanotubes polymerized with a layer of molecularly imprinted PMAA

Po Yen Chen, Chia-Yu Lin, Kuo Chuan Ho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A molecularly imprinted poly-metharylic acid (PMAA), polymerizing on the surface of multi-walled carbon nanotube (MWCNT), was synthesized. The MWCNT was modified by a layer of carboxylic acid and reacted with EDC and NHS to activate the carboxylic acid, which was prepared for the purpose of bonding allyl amine and getting an unsaturated side chain (-C=C). The resultant structure is abbreviated as MWCNTs-CH=CH2. It is well known that the vinyl group side chain provides good attachment between the MWCNTs and the molecularly imprinted polymer (MIP). The MIP based on PMAA was polymerized on the surface of MWCNTs-CH=CH 2 with the addition of uric acid (UA). The non-imprinted polymer (NIP) was polymerized without adding UA. The adsorbed amount of UA approached the equilibrium value upon 60 min adsorption. The adsorption isotherm was obtained by immersing 10 mg of MIP or NIP in 5 mL aqueous solution containing different concentrations of UA. The adsorbed amounts were measured via a UV-Vis spectrometer at a wavelength of 292 nm. From the adsorption isotherm, it is seen that the MIP particles possess a good imprinting efficiency of about 4.41.

Original languageEnglish
Title of host publicationOlfaction and Electronic Nose - Proceedings of the 13th International Symposium on Olfaction and Electronic Nose, ISOEN
Pages284-287
Number of pages4
DOIs
Publication statusPublished - 2009 Nov 27
Event13th International Symposium on Olfaction and Electronic Nose, ISOEN - Brescia, Italy
Duration: 2009 Apr 152009 Apr 17

Publication series

NameAIP Conference Proceedings
Volume1137
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other13th International Symposium on Olfaction and Electronic Nose, ISOEN
CountryItaly
CityBrescia
Period09-04-1509-04-17

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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