Detection of Y-chromosome sequences in patients with X-chromosome abnormalities.

P. L. Kuo, R. C. Wu, S. J. Lin, C. C. Tzeng, H. S. Liu, K. E. Huang

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The polymerase chain reaction was used to test 18 adults and eight fetuses with numerical or structural X-chromosome abnormalities for the presence of nine Y-specific loci. Y-chromosomal DNA was detectable in one adult patient with X-chromosome mosaicism. This study and previous reports provide evidence to support further screening of patients with X-chromosome abnormalities for the presence of Y-chromosomal DNA sequences. Long-term follow-up of patients with Y-chromosomal sequences is required to determine the risk of gonadal neoplasms and other abnormal phenotypes.

Original languageEnglish
Pages (from-to)529-534
Number of pages6
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume94
Issue number9
Publication statusPublished - 1995 Sep

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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