Detection of Y-chromosome sequences in patients with X-chromosome abnormalities.

Pao-Lin Kuo, R. C. Wu, S. J. Lin, C. C. Tzeng, Hsiao-Sheng Liu, K. E. Huang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The polymerase chain reaction was used to test 18 adults and eight fetuses with numerical or structural X-chromosome abnormalities for the presence of nine Y-specific loci. Y-chromosomal DNA was detectable in one adult patient with X-chromosome mosaicism. This study and previous reports provide evidence to support further screening of patients with X-chromosome abnormalities for the presence of Y-chromosomal DNA sequences. Long-term follow-up of patients with Y-chromosomal sequences is required to determine the risk of gonadal neoplasms and other abnormal phenotypes.

Original languageEnglish
Pages (from-to)529-534
Number of pages6
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume94
Issue number9
Publication statusPublished - 1995 Jan 1

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Y Chromosome
X Chromosome
Chromosome Aberrations
Mosaicism
Fetus
Phenotype
Polymerase Chain Reaction
DNA
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kuo, Pao-Lin ; Wu, R. C. ; Lin, S. J. ; Tzeng, C. C. ; Liu, Hsiao-Sheng ; Huang, K. E. / Detection of Y-chromosome sequences in patients with X-chromosome abnormalities. In: Journal of the Formosan Medical Association = Taiwan yi zhi. 1995 ; Vol. 94, No. 9. pp. 529-534.
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Detection of Y-chromosome sequences in patients with X-chromosome abnormalities. / Kuo, Pao-Lin; Wu, R. C.; Lin, S. J.; Tzeng, C. C.; Liu, Hsiao-Sheng; Huang, K. E.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 94, No. 9, 01.01.1995, p. 529-534.

Research output: Contribution to journalArticle

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