Determination of coagulation time in whole blood containing anticoagulant by piezoelectric quartz crystal sensor

Hsien-Chang Chang, Tzong Jih Cheng, Tsui Hsun Wu, Tsun Mei Lin

Research output: Contribution to journalConference article

14 Citations (Scopus)

Abstract

A piezoelectric quartz crystal (PQC) system possessing an adequate sensitivity to a slight change of viscosity was previously employed to monitor blood coagulation. Here, the activated partial thromboplastin time (aPTT), clotting time (CT) for platelet poor plasma (PPP), and whole blood were evaluated using PQC system, the results showed a good agreement with the aPTT results measured by optical coagulometer (OC). As a result, a good linear relationship for heparin concentration from 0 to 1 unit/ml introduced in both of the specimens could be obtained in PQC and OC systems.

Original languageEnglish
Pages (from-to)296-298
Number of pages3
JournalSensors and Actuators, B: Chemical
Volume66
Issue number1
DOIs
Publication statusPublished - 2000 Jul 25
EventIMCS-7: 7th International Meeting on Chemical Sensors - Beijing, China
Duration: 1998 Jul 271998 Jul 30

Fingerprint

anticoagulants
piezoelectric crystals
Quartz
thromboplastin
coagulation
Coagulation
quartz crystals
Anticoagulants
blood
Blood
Thromboplastin
Crystals
sensors
Sensors
blood coagulation
clotting
heparins
Platelets
platelets
Optical systems

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this

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abstract = "A piezoelectric quartz crystal (PQC) system possessing an adequate sensitivity to a slight change of viscosity was previously employed to monitor blood coagulation. Here, the activated partial thromboplastin time (aPTT), clotting time (CT) for platelet poor plasma (PPP), and whole blood were evaluated using PQC system, the results showed a good agreement with the aPTT results measured by optical coagulometer (OC). As a result, a good linear relationship for heparin concentration from 0 to 1 unit/ml introduced in both of the specimens could be obtained in PQC and OC systems.",
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Determination of coagulation time in whole blood containing anticoagulant by piezoelectric quartz crystal sensor. / Chang, Hsien-Chang; Cheng, Tzong Jih; Wu, Tsui Hsun; Lin, Tsun Mei.

In: Sensors and Actuators, B: Chemical, Vol. 66, No. 1, 25.07.2000, p. 296-298.

Research output: Contribution to journalConference article

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