Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon

Guan Chun Chen, Jian Xing Wu, Yi Chun Du, Chia Hung Lin, Pei Jarn Chen, Tainsong Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Achilles tendon (AT) is the most fragile and vulnerable part in human body. Stress-strain properties and shape changing such as cross-sectional area variations of this tendon are important biomechanical properties used clinically for assessing and monitoring surgical repair or postoperative healing progress. However, so far, there are few methods for non-invasively, precisely and quantitatively assessing in vivo AT mechanism. In this study, we develop a quantitative ultrasound system (QUS) based on FPGA aiming at estimating stress-strain properties of AT via evaluating the broadband ultrasound attenuation (BUA) parameter upon different levels of applied stress on the AT. Twenty fresh ATs of hind porcine trotters were procured from a local abattoir, and were preloaded for 30 cycles with a cyclic loading ranging from 0 to 300 N. The loading force pulled along the tendon fibers, and the changes of AT cross-sectional area were acquired by ultrasound transducer implemented in the palmardorsal direction which was perpendicular to the tendon fibers. BUA has been widely used to estimate the broadband ultrasonic attenuation (dB MHz-1) by calculating the slope of a linear regression fit to the attenuation against frequency plot within a frequency range. The tendons were then strained from 1 to 400 N with single steps of 50 N, and the measurements were repeated for ten times following calculating the average slope of BUA to reduce the interference of noise. Results showed that as the tendon tissue was stretched orthogonally to the beam axis, BUA coefficient decreased linearly with increasing stress (R-square =0.89). This indicated that the BUA coefficient is a potentially useful parameter for quantitative characterization of ATs. The FPGA system proposed for measuring tendon thickness using QUS technique is an easy and objective method to precisely evaluate the tissue thickness, providing a new way for AT to implement high-speed online diagnosis.

Original languageEnglish
Title of host publicationIEEE International Ultrasonics Symposium, IUS
PublisherIEEE Computer Society
Pages2430-2433
Number of pages4
ISBN (Electronic)9781479970490
DOIs
Publication statusPublished - 2014 Oct 20
Event2014 IEEE International Ultrasonics Symposium, IUS 2014 - Chicago, United States
Duration: 2014 Sep 32014 Sep 6

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2014 IEEE International Ultrasonics Symposium, IUS 2014
CountryUnited States
CityChicago
Period14-09-0314-09-06

Fingerprint

tendons
broadband
attenuation
attenuation coefficients
slopes
fibers
healing
human body
regression analysis
transducers
estimating

All Science Journal Classification (ASJC) codes

  • Acoustics and Ultrasonics

Cite this

Chen, G. C., Wu, J. X., Du, Y. C., Lin, C. H., Chen, P. J., & Chen, T. (2014). Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon. In IEEE International Ultrasonics Symposium, IUS (pp. 2430-2433). [6931769] (IEEE International Ultrasonics Symposium, IUS). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2014.0606
Chen, Guan Chun ; Wu, Jian Xing ; Du, Yi Chun ; Lin, Chia Hung ; Chen, Pei Jarn ; Chen, Tainsong. / Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon. IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society, 2014. pp. 2430-2433 (IEEE International Ultrasonics Symposium, IUS).
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abstract = "Achilles tendon (AT) is the most fragile and vulnerable part in human body. Stress-strain properties and shape changing such as cross-sectional area variations of this tendon are important biomechanical properties used clinically for assessing and monitoring surgical repair or postoperative healing progress. However, so far, there are few methods for non-invasively, precisely and quantitatively assessing in vivo AT mechanism. In this study, we develop a quantitative ultrasound system (QUS) based on FPGA aiming at estimating stress-strain properties of AT via evaluating the broadband ultrasound attenuation (BUA) parameter upon different levels of applied stress on the AT. Twenty fresh ATs of hind porcine trotters were procured from a local abattoir, and were preloaded for 30 cycles with a cyclic loading ranging from 0 to 300 N. The loading force pulled along the tendon fibers, and the changes of AT cross-sectional area were acquired by ultrasound transducer implemented in the palmardorsal direction which was perpendicular to the tendon fibers. BUA has been widely used to estimate the broadband ultrasonic attenuation (dB MHz-1) by calculating the slope of a linear regression fit to the attenuation against frequency plot within a frequency range. The tendons were then strained from 1 to 400 N with single steps of 50 N, and the measurements were repeated for ten times following calculating the average slope of BUA to reduce the interference of noise. Results showed that as the tendon tissue was stretched orthogonally to the beam axis, BUA coefficient decreased linearly with increasing stress (R-square =0.89). This indicated that the BUA coefficient is a potentially useful parameter for quantitative characterization of ATs. The FPGA system proposed for measuring tendon thickness using QUS technique is an easy and objective method to precisely evaluate the tissue thickness, providing a new way for AT to implement high-speed online diagnosis.",
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Chen, GC, Wu, JX, Du, YC, Lin, CH, Chen, PJ & Chen, T 2014, Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon. in IEEE International Ultrasonics Symposium, IUS., 6931769, IEEE International Ultrasonics Symposium, IUS, IEEE Computer Society, pp. 2430-2433, 2014 IEEE International Ultrasonics Symposium, IUS 2014, Chicago, United States, 14-09-03. https://doi.org/10.1109/ULTSYM.2014.0606

Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon. / Chen, Guan Chun; Wu, Jian Xing; Du, Yi Chun; Lin, Chia Hung; Chen, Pei Jarn; Chen, Tainsong.

IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society, 2014. p. 2430-2433 6931769 (IEEE International Ultrasonics Symposium, IUS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Chen GC, Wu JX, Du YC, Lin CH, Chen PJ, Chen T. Development of a FPGA-based quantitative ultrasound system for assessing stress-strain properties of Achilles tendon. In IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society. 2014. p. 2430-2433. 6931769. (IEEE International Ultrasonics Symposium, IUS). https://doi.org/10.1109/ULTSYM.2014.0606