Development of brain focal cooling measurement for induced epilepsy

Kuan Chou Hou, Chih Wei Chang, Chun Ying Lin, Jin Chern Chiou, Yu Hsing Huang, Fu Zen Shaw

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cooling is a potential treatment for induced epilepsy. There is no electric current pass through the organization of brain because it will damage it with high temperature. EEG electrodes and thermal electric (TE) coolers were integrated and placed in the head of rat. EEG electrodes were used to measure brain waveform and TE cooler was employed to be a cooling actuator to decrease temperature on the surface of cortex. Brain cortex can be cooled down lower than body temperature in order to suppress epilepsy and variance of temperature do not exceed over ± 2 °C. The experiment for suppressing epilepsy was implemented and brain waveforms of induced epilepsy were detected. Suppression with focal cooling is the main technology for the current study. We are currently determining the efficacy for the therapy of certain focal epilepsies.

Original languageEnglish
Title of host publicationNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Pages603-606
Number of pages4
DOIs
Publication statusPublished - 2011 Oct 4
Event6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan
Duration: 2011 Feb 202011 Feb 23

Publication series

NameNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Other

Other6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
CountryTaiwan
CityKaohsiung
Period11-02-2011-02-23

Fingerprint

epilepsy
brain
cooling
electroencephalography
cortexes
coolers
waveforms
body temperature
electrodes
electric current
rats
therapy
actuators
retarding
damage
temperature

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

Cite this

Hou, K. C., Chang, C. W., Lin, C. Y., Chiou, J. C., Huang, Y. H., & Shaw, F. Z. (2011). Development of brain focal cooling measurement for induced epilepsy. In NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (pp. 603-606). [6017427] (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017427
Hou, Kuan Chou ; Chang, Chih Wei ; Lin, Chun Ying ; Chiou, Jin Chern ; Huang, Yu Hsing ; Shaw, Fu Zen. / Development of brain focal cooling measurement for induced epilepsy. NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 2011. pp. 603-606 (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems).
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abstract = "Cooling is a potential treatment for induced epilepsy. There is no electric current pass through the organization of brain because it will damage it with high temperature. EEG electrodes and thermal electric (TE) coolers were integrated and placed in the head of rat. EEG electrodes were used to measure brain waveform and TE cooler was employed to be a cooling actuator to decrease temperature on the surface of cortex. Brain cortex can be cooled down lower than body temperature in order to suppress epilepsy and variance of temperature do not exceed over ± 2 °C. The experiment for suppressing epilepsy was implemented and brain waveforms of induced epilepsy were detected. Suppression with focal cooling is the main technology for the current study. We are currently determining the efficacy for the therapy of certain focal epilepsies.",
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Hou, KC, Chang, CW, Lin, CY, Chiou, JC, Huang, YH & Shaw, FZ 2011, Development of brain focal cooling measurement for induced epilepsy. in NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems., 6017427, NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, pp. 603-606, 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011, Kaohsiung, Taiwan, 11-02-20. https://doi.org/10.1109/NEMS.2011.6017427

Development of brain focal cooling measurement for induced epilepsy. / Hou, Kuan Chou; Chang, Chih Wei; Lin, Chun Ying; Chiou, Jin Chern; Huang, Yu Hsing; Shaw, Fu Zen.

NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 2011. p. 603-606 6017427 (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Hou KC, Chang CW, Lin CY, Chiou JC, Huang YH, Shaw FZ. Development of brain focal cooling measurement for induced epilepsy. In NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 2011. p. 603-606. 6017427. (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017427