We give a brief historical perspective of IFToMM China-Taipei activities in mechanism and machine science and its involvement in the IFToMM World Congress. The systematic generation of all possible mechanisms for required topological characteristics with design requirement and constraints was proposed by H. S. Yang in 1980 by the so-called “Methodology for the Conceptual Design of Mechanisms”. The gearing machines, such as CNC hobbing, shaving, grinding, and hypoid gear generator have been developed in Taiwan with aid of IFToMM China-Taipei community. For classification of geared mechanisms, a methodology is developed using concept of kinematic fractionation. Finally the tendon drive mechanism and nanometer positioning mechanism are included.