Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume

Hung Yi Chen, Qiaole Zhao, Kuei Ling Su, Yu-Cheng Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

This paper reports a transdermal delivery chip system for delivering gold nanoparticles (AuNPs) into human stratum corneum (HSC). The proposed transdermal delivery chip system could provide electrostatic force to drive AuNPs which were then delivered into HSC via Intercellular route. Various DC voltages (3, 6, and 9 V) were employed to generate electric field of different intensities (3.2∼9.8 V/cm) as a role to drive AuNPs Into HSC. Results show permeability of the skin Increases with the electric field intensities. We use MEMS technology to design and fabricate the proposed chip system. The proposed transdermal delivery chip system will provide many potential usages for blomedical applications.

Original languageEnglish
Title of host publication3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008
Pages996-999
Number of pages4
DOIs
Publication statusPublished - 2008 Sep 1
Event3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008 - Sanya, China
Duration: 2008 Jan 62008 Jan 9

Publication series

Name3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS

Other

Other3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008
CountryChina
CitySanya
Period08-01-0608-01-09

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Electrical and Electronic Engineering

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