Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume

Hung Yi Chen; Qiaole Zhao; Kuei Ling Su; Yu-Cheng Lin

doi:10.1109/NEMS.2008.4484489

Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume

Hung Yi Chen, Qiaole Zhao, Kuei Ling Su, Yu-Cheng Lin

Department of Engineering Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper reports a transdermal delivery chip system for delivering gold nanoparticles (AuNPs) into human stratum corneum (HSC). The proposed transdermal delivery chip system could provide electrostatic force to drive AuNPs which were then delivered into HSC via Intercellular route. Various DC voltages (3, 6, and 9 V) were employed to generate electric field of different intensities (3.2∼9.8 V/cm) as a role to drive AuNPs Into HSC. Results show permeability of the skin Increases with the electric field intensities. We use MEMS technology to design and fabricate the proposed chip system. The proposed transdermal delivery chip system will provide many potential usages for blomedical applications.

Original language	English
Title of host publication	3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008
Pages	996-999
Number of pages	4
DOIs	https://doi.org/10.1109/NEMS.2008.4484489
Publication status	Published - 2008 Sept 1
Event	3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008 - Sanya, China Duration: 2008 Jan 6 → 2008 Jan 9

Publication series

Name	3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS

Other

Other	3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008
Country/Territory	China
City	Sanya
Period	08-01-06 → 08-01-09

All Science Journal Classification (ASJC) codes

Control and Systems Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/NEMS.2008.4484489

Cite this

Chen, H. Y., Zhao, Q., Su, K. L., & Lin, Y.-C. (2008). Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume. In 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008 (pp. 996-999). Article 4484489 (3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS). https://doi.org/10.1109/NEMS.2008.4484489

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title = "Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume",

abstract = "This paper reports a transdermal delivery chip system for delivering gold nanoparticles (AuNPs) into human stratum corneum (HSC). The proposed transdermal delivery chip system could provide electrostatic force to drive AuNPs which were then delivered into HSC via Intercellular route. Various DC voltages (3, 6, and 9 V) were employed to generate electric field of different intensities (3.2∼9.8 V/cm) as a role to drive AuNPs Into HSC. Results show permeability of the skin Increases with the electric field intensities. We use MEMS technology to design and fabricate the proposed chip system. The proposed transdermal delivery chip system will provide many potential usages for blomedical applications.",

author = "Chen, {Hung Yi} and Qiaole Zhao and Su, {Kuei Ling} and Yu-Cheng Lin",

year = "2008",

month = sep,

day = "1",

doi = "10.1109/NEMS.2008.4484489",

language = "English",

isbn = "9781424419081",

series = "3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS",

pages = "996--999",

booktitle = "3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008",

note = "3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008 ; Conference date: 06-01-2008 Through 09-01-2008",

}

Chen, HY, Zhao, Q, Su, KL & Lin, Y-C 2008, Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume. in 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008., 4484489, 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS, pp. 996-999, 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008, Sanya, China, 08-01-06. https://doi.org/10.1109/NEMS.2008.4484489

Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume. / Chen, Hung Yi; Zhao, Qiaole; Su, Kuei Ling et al.
3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008. 2008. p. 996-999 4484489 (3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - Development of transdermal delivery chip system

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AU - Chen, Hung Yi

AU - Zhao, Qiaole

AU - Su, Kuei Ling

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PY - 2008/9/1

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N2 - This paper reports a transdermal delivery chip system for delivering gold nanoparticles (AuNPs) into human stratum corneum (HSC). The proposed transdermal delivery chip system could provide electrostatic force to drive AuNPs which were then delivered into HSC via Intercellular route. Various DC voltages (3, 6, and 9 V) were employed to generate electric field of different intensities (3.2∼9.8 V/cm) as a role to drive AuNPs Into HSC. Results show permeability of the skin Increases with the electric field intensities. We use MEMS technology to design and fabricate the proposed chip system. The proposed transdermal delivery chip system will provide many potential usages for blomedical applications.

AB - This paper reports a transdermal delivery chip system for delivering gold nanoparticles (AuNPs) into human stratum corneum (HSC). The proposed transdermal delivery chip system could provide electrostatic force to drive AuNPs which were then delivered into HSC via Intercellular route. Various DC voltages (3, 6, and 9 V) were employed to generate electric field of different intensities (3.2∼9.8 V/cm) as a role to drive AuNPs Into HSC. Results show permeability of the skin Increases with the electric field intensities. We use MEMS technology to design and fabricate the proposed chip system. The proposed transdermal delivery chip system will provide many potential usages for blomedical applications.

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Chen HY, Zhao Q, Su KL, Lin YC. Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume. In 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008. 2008. p. 996-999. 4484489. (3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS). doi: 10.1109/NEMS.2008.4484489

Development of transdermal delivery chip system: Deliver gold nanoparticles into human stratum corneume

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