Directions of Deep Brain Stimulation for Epilepsy and Parkinson’s Disease

Ying Chang Wu, Ying Siou Liao, Wen Hsiu Yeh, Sheng Fu Liang, Fu Zen Shaw

Research output: Contribution to journalReview articlepeer-review

21 Citations (Scopus)


Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders and neurological/psychiatric disorders. DBS has been approved for the control of Parkinson disease (PD) and epilepsy. Objectives: A systematic review and possible future direction of DBS system studies is performed in the open loop and closed-loop configuration on PD and epilepsy. Methods: We searched Google Scholar database for DBS system and development. DBS search results were categorized into clinical device and research system from the open-loop and closed-loop perspectives. Results: We performed literature review for DBS on PD and epilepsy in terms of system development by the open loop and closed-loop configuration. This study described development and trends for DBS in terms of electrode, recording, stimulation, and signal processing. The closed-loop DBS system raised a more attention in recent researches. Conclusion: We overviewed development and progress of DBS. Our results suggest that the closed-loop DBS is important for PD and epilepsy.

Original languageEnglish
Article number680938
JournalFrontiers in Neuroscience
Publication statusPublished - 2021 Jun 14

All Science Journal Classification (ASJC) codes

  • General Neuroscience


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