Abstract
Original language | English |
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Patent number | 7943728 |
Publication status | Published - 2008 Aug 7 |
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DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF. / Chuang, Woei-Jer (Inventor).
Patent No.: 7943728.Research output: Patent
TY - PAT
T1 - DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF
AU - Chuang, Woei-Jer
PY - 2008/8/7
Y1 - 2008/8/7
N2 - Disintegrin variants and pharmaceutical uses thereof are disclosed. The disintegrin variant includes an isolated polypeptide that has integrin .alpha.v.beta.3 receptor-antagonist activity and substantially reduced integrin .alpha.llb.beta.3 and/or .alpha.5.beta.1 receptor-blocking activity as compared to a wild-type disintegrin.
AB - Disintegrin variants and pharmaceutical uses thereof are disclosed. The disintegrin variant includes an isolated polypeptide that has integrin .alpha.v.beta.3 receptor-antagonist activity and substantially reduced integrin .alpha.llb.beta.3 and/or .alpha.5.beta.1 receptor-blocking activity as compared to a wild-type disintegrin.
M3 - Patent
M1 - 7943728
ER -