TY - JOUR
T1 - Disseminated Mycobacterium szulgai infection in a patient with anti-interferon-gamma autoantibodies
AU - Weng, Tzu Ping
AU - Syue, Ling Shan
AU - Lee, Nan Yao
N1 - Funding Information:
Financial support. This study was supported by the grants from National Cheng Kung University Hospital , Tainan, Taiwan (NCKUH- 10902060 ).
Publisher Copyright:
© 2020
PY - 2020
Y1 - 2020
N2 - Incidence of nontuberculous mycobacterial infections has increased during the past decades. Disseminated infections are relatively rare and associated with immunocompromised status. We report a case of disseminated Mycobacterium szulgai infection of cervical lymphadenitis and pulmonary involvement with positive anti-interferon-gamma autoantibodies. The patient was successfully treated with rifampin, ethambutol, and clarithromycin. The case reports and series through search engines of Pubmed and Google with the keyword of disseminated infection of M. szulgai were reviewed. Fifteen patients of disseminated M. szulgai infection were reviewed and included. Disseminated M. szulgai infection involves bone, skin and lymph node more common instead of pulmonary involvement, and most are associated with immunocompromised status with neoplastic hematologic disorders. In patients with disseminated M. szulgai infection, long term anti-mycobacterial agents are necessary. Most patients will respond to rifampin and ethambutol combination regimens.
AB - Incidence of nontuberculous mycobacterial infections has increased during the past decades. Disseminated infections are relatively rare and associated with immunocompromised status. We report a case of disseminated Mycobacterium szulgai infection of cervical lymphadenitis and pulmonary involvement with positive anti-interferon-gamma autoantibodies. The patient was successfully treated with rifampin, ethambutol, and clarithromycin. The case reports and series through search engines of Pubmed and Google with the keyword of disseminated infection of M. szulgai were reviewed. Fifteen patients of disseminated M. szulgai infection were reviewed and included. Disseminated M. szulgai infection involves bone, skin and lymph node more common instead of pulmonary involvement, and most are associated with immunocompromised status with neoplastic hematologic disorders. In patients with disseminated M. szulgai infection, long term anti-mycobacterial agents are necessary. Most patients will respond to rifampin and ethambutol combination regimens.
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U2 - 10.1016/j.idcr.2020.e00848
DO - 10.1016/j.idcr.2020.e00848
M3 - Article
AN - SCOPUS:85085757056
SN - 2214-2509
VL - 21
JO - IDCases
JF - IDCases
M1 - e00848
ER -