Does arsenic exposure increase the risk for diabetes mellitus?

Hui Fen Chiu, Chih Ching Chang, Shang Shyue Tsai, Chun Yuh Yang

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


OBJECTIVE: Long-term arsenic exposure has been reported to associated with prevalence, incidence, and mortality of diabetes mellitus (DM). A tap water supply system was implemented in the early 1960s in the blackfoot disease (BFD) endemic areas. The objective of this study is to examine whether DM mortality decreased after the improvement of drinking water supply system through elimination of arsenic exposure from artesian well water. METHODS: Standardized mortality ratios (SMRs) for DM were calculated for the BFD endemic area for the years 1971-2000. RESULTS: The study results show that mortality from DM declined in females (but not in males) gradually after the improvement of drinking water supply system. CONCLUSIONS: Based on the reversibility criterion, the association between arsenic exposure and DM is likely to be casual for females but not in males.

Original languageEnglish
Pages (from-to)63-67
Number of pages5
JournalJournal of Occupational and Environmental Medicine
Issue number1
Publication statusPublished - 2006 Jan

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health


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