TY - JOUR
T1 - Does conductance catheter measurement system give consistent and reliable pressure-volume relations in rats
AU - Wei, Chia Ling
AU - Kan, Chung Dann
AU - Wang, Jieh Neng
AU - Wang, Yi Wen
AU - Chen, Chin Hong
AU - Tsai, Mei Ling
N1 - Funding Information:
Manuscript received September 7, 2010; revised November 11, 2010 and December 27, 2010; accepted January 30, 2011. Date of publication February 22, 2011; date of current version May 18, 2011. This work was supported in part by the National Science Council, Taiwan, under Grants NSC-95-2218-E-006-038, NSC-97-2314-B-006-018-MY2, and NSC-99-2220-E-006-004. Asterisk indicates corresponding author.
PY - 2011/6
Y1 - 2011/6
N2 - The conductance catheter technique was developed in the 1980s to measure instantaneous ventricular conductance. After converting measured conductance to volume signals by use of the classic Baan conductance-to-volume equation, real-time pressurevolume (PV) relations can be obtained. A nonlinear conductance-to-volume conversion equation was proposed by Wei in 2005 to improve the accuracy of the conductance catheter system. This study tested the in vivo applicability of the nonlinear conversion equation, particularly focusing on the effect of deviation in catheter position. By altering catheter position, PV loops obtained by using the classic Baans equation and the nonlinear equation were compared. The comparison results show that the nonlinear equation indeed compensates for the errors introduced by catheter position deviation, and gives more consistent and reliable PV relations. Moreover, the effect of variations in blood resistivity was analyzed. To obtain consistent and reliable PV relations, the nonlinear equation is suggested for use, and changes in blood resistivity should be carefully monitored.
AB - The conductance catheter technique was developed in the 1980s to measure instantaneous ventricular conductance. After converting measured conductance to volume signals by use of the classic Baan conductance-to-volume equation, real-time pressurevolume (PV) relations can be obtained. A nonlinear conductance-to-volume conversion equation was proposed by Wei in 2005 to improve the accuracy of the conductance catheter system. This study tested the in vivo applicability of the nonlinear conversion equation, particularly focusing on the effect of deviation in catheter position. By altering catheter position, PV loops obtained by using the classic Baans equation and the nonlinear equation were compared. The comparison results show that the nonlinear equation indeed compensates for the errors introduced by catheter position deviation, and gives more consistent and reliable PV relations. Moreover, the effect of variations in blood resistivity was analyzed. To obtain consistent and reliable PV relations, the nonlinear equation is suggested for use, and changes in blood resistivity should be carefully monitored.
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U2 - 10.1109/TBME.2011.2118210
DO - 10.1109/TBME.2011.2118210
M3 - Article
C2 - 21342837
AN - SCOPUS:79956355267
VL - 58
SP - 1804
EP - 1813
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
SN - 0018-9294
IS - 6
M1 - 5719160
ER -