Double-microcantilever design for surface stress measurement in biosensors

T. I. Yin, S. M. Yang

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

Microcantilever sensor with embedded piezoresistor has been proposed to measure the surface stress change from biochemical reaction. However, the sensor performance is adversely influenced by the piezoresistive thermal stress and biaxial surface stress loading. A mechanics model of piezoresistive microcantilever subject to surface stress loading is developed in this paper. A double-microcantilever design composed of the top immobilized microcantilever and the bottom sensing microcantilever is also proposed such that the surface stress loading can be converted to a concentrated force loading. The effect of biaxial surface stress can thus be limited to the immobilized microcantilever with the uniaxial strain in the sensing microcantilever. Analyses show that the surface stress sensitivity can be increased by high length ratio and lower thickness ratio of the two cantilevers. More than two orders of magnitude in measurement sensitivity can be achieved and the induced thermal noise can be minimized.

Original languageEnglish
Article number51
Pages (from-to)333-344
Number of pages12
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5763
DOIs
Publication statusPublished - 2005 Oct 3
EventSmart Structures and Materials 2005 - Smart Electronics, MEMS,, BioMEMS, and Nanotechnology - San Diego, CA, United States
Duration: 2005 Mar 72005 Mar 10

Fingerprint

Biosensor
stress measurement
Stress measurement
Surface measurement
bioinstrumentation
Biosensors
Biaxial
Sensing
Sensor
Thermal noise
thickness ratio
axial strain
Thermal Stress
sensors
Cantilever
thermal noise
Sensors
thermal stresses
Thermal stress
Mechanics

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

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title = "Double-microcantilever design for surface stress measurement in biosensors",
abstract = "Microcantilever sensor with embedded piezoresistor has been proposed to measure the surface stress change from biochemical reaction. However, the sensor performance is adversely influenced by the piezoresistive thermal stress and biaxial surface stress loading. A mechanics model of piezoresistive microcantilever subject to surface stress loading is developed in this paper. A double-microcantilever design composed of the top immobilized microcantilever and the bottom sensing microcantilever is also proposed such that the surface stress loading can be converted to a concentrated force loading. The effect of biaxial surface stress can thus be limited to the immobilized microcantilever with the uniaxial strain in the sensing microcantilever. Analyses show that the surface stress sensitivity can be increased by high length ratio and lower thickness ratio of the two cantilevers. More than two orders of magnitude in measurement sensitivity can be achieved and the induced thermal noise can be minimized.",
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Double-microcantilever design for surface stress measurement in biosensors. / Yin, T. I.; Yang, S. M.

In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 5763, 51, 03.10.2005, p. 333-344.

Research output: Contribution to journalConference article

TY - JOUR

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AU - Yin, T. I.

AU - Yang, S. M.

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N2 - Microcantilever sensor with embedded piezoresistor has been proposed to measure the surface stress change from biochemical reaction. However, the sensor performance is adversely influenced by the piezoresistive thermal stress and biaxial surface stress loading. A mechanics model of piezoresistive microcantilever subject to surface stress loading is developed in this paper. A double-microcantilever design composed of the top immobilized microcantilever and the bottom sensing microcantilever is also proposed such that the surface stress loading can be converted to a concentrated force loading. The effect of biaxial surface stress can thus be limited to the immobilized microcantilever with the uniaxial strain in the sensing microcantilever. Analyses show that the surface stress sensitivity can be increased by high length ratio and lower thickness ratio of the two cantilevers. More than two orders of magnitude in measurement sensitivity can be achieved and the induced thermal noise can be minimized.

AB - Microcantilever sensor with embedded piezoresistor has been proposed to measure the surface stress change from biochemical reaction. However, the sensor performance is adversely influenced by the piezoresistive thermal stress and biaxial surface stress loading. A mechanics model of piezoresistive microcantilever subject to surface stress loading is developed in this paper. A double-microcantilever design composed of the top immobilized microcantilever and the bottom sensing microcantilever is also proposed such that the surface stress loading can be converted to a concentrated force loading. The effect of biaxial surface stress can thus be limited to the immobilized microcantilever with the uniaxial strain in the sensing microcantilever. Analyses show that the surface stress sensitivity can be increased by high length ratio and lower thickness ratio of the two cantilevers. More than two orders of magnitude in measurement sensitivity can be achieved and the induced thermal noise can be minimized.

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